Evidence map›Paper›PMID 41693363›Full record

ArticleDevelopment and psychopathology2026

The role of negative affectivity in the developmental pathway linking perinatal complications to behavioral and emotional problems in children.

Xiaoye Xu, Lauren C Shuffrey, Theresa M Bastain, Chang Liu, Rosalind J Wright, Michelle Bosquet Enlow, Alexis Hernandez, Jody Ganiban, Sara S Nozadi, Amy E Margolis and 2 more

Abstract read
In one paragraph

Article in Development and psychopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoye XuDepartment of Psychology, The State University of New York at Cortland, USA.
Lauren C ShuffreyDepartment of Child and Adolescent Psychiatry, NYU Grossman School of Medicine, USA.ORCID https://orcid.org/0000-0003-3631-5971
Theresa M BastainDepartment of Population and Public Health Sciences, University of Southern California, USA.
Chang LiuDepartment of Psychology, Washington State University, USA.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, USA.
Michelle Bosquet EnlowDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, USA.ORCID https://orcid.org/0000-0003-2598-3894
Alexis HernandezDepartment of Psychology, University of Southern Californiahttps://ror.org/03taz7m60, USA.ORCID https://orcid.org/0000-0001-5015-1905
Jody GanibanDepartment of Psychological & Brain Sciences, George Washington University, USA.ORCID https://orcid.org/0000-0001-5908-6644
Sara S NozadiPharmaceutical Sciences, The University of New Mexico Health Sciences Center, USA.
Amy E MargolisDepartment of Psychiatry and Behavioral Health, The Ohio State University, USA.
Amy J ElliottAvera Research Institute, USA.
Santiago MoralesDepartment of Psychology, University of Southern Californiahttps://ror.org/03taz7m60, USA.ORCID https://orcid.org/0000-0002-9850-042X

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Environmental Influences on Childhood Outcomes in the Northern Plains Safe Passage Study CohortsUH3OD023279 · OD · AVERA MCKENNAN · PI Amy J Elliott, Christine W Hockett · 2018 to 2026
$31.7M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
Early Life Exposure to Endocrine Disrupting Chemicals and Child Growth, Adiposity, and NeurodevelopmentUH3OD023289 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI ASSIAMIRA FERRARA, Monique Marie Hedderson · 2018 to 2026
$25.1M
Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Environmental Influences on Child Health Outcomes in Puerto Rico (ECHO-PRO)UH3OD023251 · OD · NORTHEASTERN UNIVERSITY · PI Akram N Alshawabkeh · 2018 to 2026
$24.0M
Understanding Risk Gradients from Environment on Native American Child Health Trajectories: Toxicants, Immunomodulation, Metabolic syndromes, & Metals ExposureUH3OD023344 · OD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Johnnye L Lewis, Debra MacKenzie · 2019 to 2026
$21.1M
NCATS NIH HHS UL1 TR004419NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023279NIH HHS UG3 OD023313NIH HHS UG3 OD023318NIH HHS UH3 OD023248NIH HHS UH3 OD023249NIH HHS UH3 OD023251NIH HHS UH3 OD023272NIH HHS UH3 OD023279NIH HHS UH3 OD023285NIH HHS UH3 OD023287NIH HHS UH3 OD023288NIH HHS UH3 OD023289NIH HHS UH3 OD023290NIH HHS UH3 OD023305NIH HHS UH3 OD023313NIH HHS UH3 OD023318NIH HHS UH3 OD023320NIH HHS UH3 OD023328NIH HHS UH3 OD023337NIH HHS UH3 OD023344NIH HHS UH3 OD023349NIH HHS UH3 OD023389
6 · The paper itself

Abstract

Although temperamental negative affectivity has been identified as a developmental mechanism mediating the link between perinatal risk and internalizing problems in early childhood, its role in predicting broader behavioral and emotional problems across childhood remains understudied. We examined the longitudinal relations among perinatal complications (i.e., prenatal maternal depression and cardiometabolic complications, preterm birth, and low birth weight), children's negative affectivity (

Indexed as

emotional and behavioral problemsmediationnegative affectivityperinatal complications

Identifiers

PMID41693363
PMCPMC12994220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.