Evidence map›Paper›PMID 41693349›Full record

ArticleHuman vaccines & immunotherapeutics2026

Impact of the two-dose varicella vaccination recommendation program and surveillance optimization on epidemiological trends in a megacity in China.

Yang Liu, Jiangning Xu, Hang Zhang, Jiawei Xu, Yuanyuan Zhang, Qing Wang, Hengqing Ji, Chunbei Zhou, Ning Yao

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang LiuEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Jiangning XuDepartment of Medical Technology, Chongqing Medical and Pharmaceutical College, Chongqing, China.
Hang ZhangDepartment of Immunization Program, Kaizhou District Center for Disease Control and Prevention, Chongqing, China.
Jiawei XuEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Yuanyuan ZhangEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Qing WangEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Hengqing JiEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Chunbei ZhouEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Ning YaoEPI Department, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.ORCID 0000-0001-9684-3018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the impact of implementing a two-dose varicella vaccine (VarV) immunization recommendation program on the incidence of varicella in Chongqing, China. Monthly reported varicella cases from 2011 to 2023 were extracted from the National Notifiable Diseases Reporting System (NNDRS), alongside the vaccination records from the Chongqing Immunization Planning Information Management System. The interrupted time series analysis (ITS) was employed to study the epidemiological trends of varicella. The average reported annual incidence of varicella in Chongqing was 69.6 per 100,000 population during 2011-2023, with the highest incidence recorded in 2019 (133.9 per 100,000 population) and the lowest in 2011 (21.3 per 100,000 population). Children aged 5-9 y accounted for 34.5% of the total cases. Second-dose coverage of VarV surged from 4.1% in 2018 to 27.5% in 2023 among children aged 4-6 y. The segmented regression model demonstrated that, following the incorporation of varicella into the surveillance system in 2014, there was an upward long-term trend in the reported varicella incidence (β

Indexed as

ChickenpoxChickenpox VaccineEpidemiological MonitoringImmunization ProgramsVaccinationAdolescentChildChild, PreschoolChinaFemaleHumansImmunization ScheduleIncidenceInfantInterrupted Time Series AnalysisMaleChickenpox Vaccineimmunization strategyinterrupted time seriessurveillancevaccineVaricella

Identifiers

PMID41693349
PMCPMC12915852

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.