Evidence map›Paper›PMID 41693088›Full record

ArticleNeurorehabilitation and neural repair2026

Motor, Cognitive, Psychological, and Neural Predictors of Concern About Falling in Persons With Multiple Sclerosis.

Taylor N Takla, Patrick G Monaghan, Maryam M Abbawi, Merrill R Landers, Hilary A Marusak, Ana M Daugherty, Nora E Fritz

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taylor N TaklaNeuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit, MI, USA.ORCID 0000-0002-6546-5752
Patrick G MonaghanNeuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit, MI, USA.ORCID 0009-0001-1151-7000
Maryam M AbbawiNeuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit, MI, USA.ORCID 0009-0003-5678-8431
Merrill R LandersDepartment of Physical Therapy, University of Nevada, Las Vegas, NV, USA.ORCID 0000-0002-4234-910X
Hilary A MarusakTranslational Neuroscience Program, Wayne State University, Detroit, MI, USA.ORCID 0000-0002-0771-6795
Ana M DaughertyTranslational Neuroscience Program, Wayne State University, Detroit, MI, USA.ORCID 0000-0002-9980-154X
Nora E FritzNeuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit, MI, USA.ORCID 0000-0002-4548-1077

Funding

Backward Walking as a Novel Fall Prediction Tool for Multiple SclerosisR21HD106133 · NICHD · WAYNE STATE UNIVERSITY · PI FRITZ, NORA E. · 2022 to 2023
$412k
Investigating Fear of Falling in Multiple Sclerosis: An Interplay of Neural, Motor, Cognitive, and Psychological FactorsF31HD116491 · NICHD · WAYNE STATE UNIVERSITY · PI TAKLA, TAYLOR · 2024 to 2025
$97k
NICHD NIH HHS F31 HD116491NICHD NIH HHS R21 HD106133
6 · The paper itself

Abstract

BackgroundConcern about falling (CAF) is highly prevalent in multiple sclerosis (MS) and is linked to poor motor, cognitive, and psychological functioning. Although CAF has been associated with impairments in these domains, the unique and combined contributions of motor, cognitive, psychological, and neural factors remain unclear. This study used a comprehensive approach to identify behavioral and neural predictors of CAF.MethodsForty-three individuals with MS completed motor, cognitive, and psychological assessments, and underwent a structural magnetic resonance imaging scan. Linear regression models examined domain-specific predictors of CAF, controlling for disease severity. A discriminant function analysis (DFA) evaluated the combined predictive value of all variables in classifying individuals into high versus low CAF groups based on a median split.ResultsCAF was significantly associated with impairments across all behavioral domains (|

Indexed as

BrainCognitive DysfunctionFatigueMultiple SclerosisAdultAnxietyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProcessing Speedcognitive impairmentsconcern about fallingmotor dysfunctionmultiple sclerosis

Identifiers

PMID41693088
PMCPMC12912773

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.