Evidence map›Paper›PMID 41692732›Full record

ArticleBMC medicine2026

Physical activity patterns and cardiovascular disease risk in adults with overweight or obesity: a prospective cohort study.

Kai Mu, Yanan Qiao, Ruilang Lin, Yongfu Yu, Min Zhao, Costan G Magnussen, Bo Xi

Abstract read
In one paragraph

Article in BMC medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai Mu *Department of Pediatrics, The Second Qilu Hospital of Shandong University, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Yanan Qiao *Department of Epidemiology, The Second Qilu Hospital of Shandong University, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Ruilang LinDepartment of Biostatistics, Key Laboratory of Public Health Safety of Ministry of Education, NHC Key Laboratory for Health Technology Assessment, School of Public Health, Fudan University, Shanghai, 200032, China.
Yongfu YuDepartment of Biostatistics, Key Laboratory of Public Health Safety of Ministry of Education, NHC Key Laboratory for Health Technology Assessment, School of Public Health, Fudan University, Shanghai, 200032, China.
Min ZhaoDepartment of Nutrition and Food Hygiene, School of Public Health, Qilu Hospital, Shandong University, Jinan, Shandong, 250012, China.
Costan G MagnussenBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Bo XiDepartment of Epidemiology, The Second Qilu Hospital of Shandong University, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. xibo2007@126.com.

Funding

China International Medical Exchange Foundation Z-2019-41-2406Jinan Science and Technology Plan-Clinical Medical Science and Technology Innovation Program 202225057National Key Research and Development Plan: Real-Time Intelligent Active Intervention on Integration of Ten Important Chronic Diseases 2020YFC2003504-2Shandong Provincial Medical Association Clinical Research Funds Qilu Special YXH2022ZX02181
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is a major global health burden, particularly among overweight and obese individuals. We aimed to investigate associations between different physical activity patterns (concentrated activity vs. regularly active) and incident CVD, and to compare their effects in this specific population.

methodsData were from the UK Biobank, with 49,368 overweight and obese individuals (63.50 ± 7.73 years; 51.4% women) included in this study from 2006-2010. Participants were categorized into three physical activity patterns: inactive (< 150 min/week of moderate-to-vigorous physical activity (MVPA)), regularly active (≥ 150 min/week of MVPA, with ≥ 50% of activity distributed over > 2 days/week), and concentrated activity (≥ 150 min/week of MVPA, with ≥ 50% concentrated on 1-2 days/week).

resultsIn fully adjusted models, both the concentrated activity and regularly active patterns had a similar magnitude of CVD risk reduction compared with inactive individuals, overall CVD (concentrated activity: HR [95% CI]: 0.79 [0.74-0.85]; regularly active: 0.76 [0.70-0.83]), myocardial infarction (concentrated activity: 0.77 [0.67-0.88]; regularly active: 0.64 [0.53-0.76]), atrial fibrillation (concentrated activity: 0.81 [0.73-0.89]; regularly active: 0.84 [0.75-0.94]), heart failure (concentrated activity: 0.60 [0.52-0.70]; regularly active: 0.61 [0.50-0.73]), and stroke (concentrated activity: 0.79 [0.66-0.94]; regularly active: 0.81 [0.65-1.00]).

conclusionsConcentrated MVPA over 1-2 days (the concentrated activity pattern) was associated with reduced CVD risk in individuals with overweight or obesity, with a magnitude of risk reduction similar to that observed for regularly distributed activity.

Indexed as

Cardiovascular DiseasesExerciseObesityOverweightAgedFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedProspective StudiesRisk FactorsUnited KingdomCardiovascular diseasesObesityPhysical activity

Identifiers

PMID41692732
PMCPMC13011554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.