Evidence map›Paper›PMID 41692723›Full record

ArticleBMC neurology2026

Suicide attempt by a patient with an early phase of progressive supranuclear palsy: a case report.

Shohei Kawai, Ryota Kobayashi, Kazutaka Sakamoto, Kiyotaka Nemoto, Daichi Morioka, Takuma Numazawa, Shinobu Kawakatsu, Yasuyuki Ohta, Akihito Suzuki

Abstract readCase Reports
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Shohei KawaiDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Ryota KobayashiDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan. ryo.kobayashi@med.id.yamagata-u.ac.jp.ORCID http://orcid.org/0000-0002-4213-618X
Kazutaka SakamotoDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Kiyotaka NemotoDepartment of Psychiatry, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Daichi MoriokaDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Takuma NumazawaDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Shinobu KawakatsuDepartment of Neuropsychiatry, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu, Japan.
Yasuyuki OhtaDepartment of Internal Medicine III, Division of Neurology and Clinical Neuroscience,, Yamagata University School of Medicine, Yamagata, Japan.
Akihito SuzukiDepartment of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuicidal ideation is reported in approximately 4% of patients with progressive supranuclear palsy (PSP); however, only three cases of PSP-related suicide attempts have been reported. Here, we report the case of a patient with early-stage PSP who attempted suicide using an organophosphorus agent. CASE PRESENTATION: An 81-year-old man with no medical history of severe depression impulsively attempted suicide by consuming an organophosphate. After improvement of the symptoms of organophosphate poisoning, the patient exhibited mild depressive mood, insomnia, mild amnesia, attention deficit, and frontal lobe dysfunction. In addition, he exhibited neck rigidity and postural instability, but no disturbance in ocular motility. Neuroradiological examination revealed findings characteristic of PSP, such as midbrain atrophy, third ventricle enlargement, and remarkably decreased dopamine transporter availability on single-photon emission computed tomography. Based on the clinical symptoms and neuroradiological findings, he was diagnosed with early-stage PSP.

conclusionsIn line with previous clinical reports and a forensic study regarding suicide and PSP, our case indicates that suicide may occur before the onset or in the early phases of PSP. Larger neuroradiological studies among older adults with signs of depression may be needed to clarify the involvement of PSP pathology in suicide.

Indexed as

Suicide, AttemptedSupranuclear Palsy, ProgressiveAged, 80 and overHumansMaleTomography, Emission-Computed, Single-PhotonArgyrophilic grain diseaseDepressionProgressive supranuclear palsySuicidal attemptSuicidal ideation

Identifiers

PMID41692723
PMCPMC13014868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.