Evidence map›Paper›PMID 41692699›Full record

ArticleJournal of sleep research2026

Delta-9-Tetrahydrocannabinol (THC) Before Bedtime: Feasibility and Mechanistic Pilot Study on Sleep and Cardiac Autonomic Activity.

Joshua E Gonzalez, Alicia V Stewart, Jacquelin L Ellison, Omar H Ordaz, LaTroy D Robinson, Noal A Clemons, Jonathan S Emens, Sean P M Rice, Steven A Shea, Nicole P Bowles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joshua E GonzalezOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.ORCID 0000-0003-0680-7852
Alicia V StewartOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Jacquelin L EllisonOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Omar H OrdazOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
LaTroy D RobinsonOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Noal A ClemonsOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Jonathan S EmensOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Sean P M RiceOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Steven A SheaOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.
Nicole P BowlesOregon Institute of Occupational Health Sciences, Oregon Health and Sciences University, Portland, Oregon, USA.

Funding

Endogenous circadian mechanisms underlying cardiovascular riskR35HL155681 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI STEVEN A SHEA · 2021 to 2026
$5.5M
Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3M
Role of the circadian rhythm on endocannabinoid response to an acute stressK01HL151745 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BOWLES, NICOLE P · 2021 to 2025
$957k
Uncovering Circadian Mechanisms of Poor Cardiometabolic HealthK01HL146992 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCHILL, ANDREW WILLIAM · 2019 to 2022
$669k
American Academy of Sleep MedicineDivision of Consumer and Business Services of the State of Oregon ORS 656.630NHLBI NIH HHS K01 HL146992NHLBI NIH HHS K01 HL151745NHLBI NIH HHS R35 HL155681NHLBI NIH HHS T32 HL083808NIH HHS K01 HL 146992NIH HHS K01 HL151745NIH HHS R35 HL 155681NIH HHS T32 HL083808
6 · The paper itself

Abstract

Disordered sleep is a common reason individuals report using cannabis, yet the physiological effects of Δ

Indexed as

Autonomic Nervous SystemDronabinolHeartHeart RateSleepActigraphyAdultFeasibility StudiesFemaleHumansMalePilot ProjectsPolysomnographySingle-Blind MethodSleep DurationYoung AdultDronabinolcannabisheart rate variabilitypolysomnographypower spectral analysisTHC

Identifiers

PMID41692699
PMCPMC13118506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.