Evidence map›Paper›PMID 41692414›Full record

ArticleVox sanguinis2026

Higher uptake of common adult vaccines in Australian blood donors: An analysis of linked registry data.

Surendra Karki, Veronica Hoad, Bette Liu, Marijke Welvaert, Rena Hirani, David O Irving

Abstract read
In one paragraph

Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Surendra KarkiAustralian Red Cross Lifeblood, Research and Development, Sydney, New South Wales, Australia.
Veronica HoadAustralian Red Cross Lifeblood, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-7827-3661
Bette LiuSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Marijke WelvaertAustralian Red Cross Lifeblood, Research and Development, Sydney, New South Wales, Australia.
Rena HiraniAustralian Red Cross Lifeblood, Research and Development, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-0371-9515
David O IrvingAustralian Red Cross Lifeblood, Research and Development, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesUnderstanding differences in blood donor vaccine uptake is essential for accurately interpreting serosurveillance of vaccine-preventable diseases and other research using donor samples and/or data. We aimed to assess vaccination uptake in donors and non-donors. MATERIALS AND

methodsWe linked the Sax Institute's 45 and Up Study data to blood donation records, the Australian Immunization Register and death records. Participants were categorized as active donors, lapsed donors or non-donors. Influenza, herpes-zoster, pneumococcal and COVID-19 vaccine uptake were analysed in the age groups recommended and eligible for free vaccination and for pertussis in the age group recommended. We calculated age- and sex-adjusted uptake percentages and differences averaged across 2021-2023, except for COVID-19 vaccine. Multivariable regression models were used to assess the association between donor status and vaccination uptake, adjusting for potential confounders.

resultsOf the 266,432 participants available for this research, 216,338 were eligible for analysis in 2021. Of these, 5734 (2.7%) were active donors, 29,237 (13.5%) were lapsed donors and 181,367 (83.8%) were non-donors. Active donors had higher vaccination uptake than non-donors (adjusted uptake ratio [95% confidence interval, CI] for influenza 1.05 [1.04, 1.06], herpes-zoster 1.20 [1.13, 1.28], pneumococcal 1.10 [1.03, 1.17], pertussis 1.09 [1.00, 1.18]), ≥2 doses of COVID-19 vaccine in 2021 1.02 [1.01, 1.02] and booster COVID-19 dose in the second half of 2023 1.08 [1.02, 1.15]. Similarly, lapsed donors had higher vaccination uptake than non-donors.

conclusionBlood donors have a higher uptake for funded/recommended adult vaccines than non-donors. These findings provide evidence of vaccination rate differences that may impact interpretation of studies where blood donor samples and/or data are used.

Indexed as

Blood DonorsRegistriesVaccinationAdolescentAdultAgedAustraliaBlood DonationFemaleHumansMaleMiddle AgedYoung Adultblood donorsserosurveillancevaccinesvaccine uptake

Identifiers

PMID41692414
PMCPMC13158012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.