Evidence map›Paper›PMID 41692096›Full record

ArticleJournal of thrombosis and haemostasis : JTH2026

National Institutes of Health funding for venous thromboembolism research.

Ryan A Coute, Jake Toy, Kameshwari Soundararajan, Benjamin von Schweinitz, Patrick J Siler, Ryan C Godwin, Ryan L Melvin

Abstract read
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan A CouteDepartment of Emergency Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA. Electronic address: rcoute@uabmc.edu.
Jake ToyLos Angeles County Emergency Medical Services Agency, Santa Fe Springs, California, USA; Department of Emergency Medicine, Harbor-University of California Los Angeles Medical Center, The Lundquist Institute, Torrance, California, USA; Department of Emergency Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.
Kameshwari SoundararajanDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.
Benjamin von SchweinitzDepartment of Emergency Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.
Patrick J SilerDepartment of Emergency Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.
Ryan C GodwinDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA; Department of Radiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.
Ryan L MelvinDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.

Funding

Improving Community-level Bystander Cardiopulmonary Resuscitation in Underserved PopulationsK23HL166692 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Ryan Andrew Coute · 2023 to 2026
$697k
NHLBI NIH HHS K23 HL166692
6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is associated with approximately 100 000 deaths annually in the United States (U.S.). Progress in the prevention, diagnosis, treatment, and recovery from VTE depends on research funding. The National Institutes of Health (NIH), the world's largest funder of biomedical research, does not currently report VTE-specific funding in its annual Categorical Spending Report.

objectivesThis study aimed to provide a descriptive analysis of NIH funding for VTE research over the past decade.

methodsWe conducted a search of the NIH Research Portfolio Online Reporting Tools Expenditures and Results database from 2015 to 2024 using a string of VTE-related search terms. Grants were categorized as VTE research (yes/no) using a large language model prompted with predefined classification criteria. We tabulated annual NIH funding amounts, the number of VTE-related grants, and the number of unique principal investigators. For 2023, VTE research investment was compared with that for heart disease and stroke, the leading causes of vascular mortality in the U.S.

resultsThe search yielded 2130 grants with complete data, of which 1114 were classified as VTE research. When excluding renewal awards, 490 unique VTE grants were identified. Total inflation-adjusted NIH funding for VTE research was $42 million in 2015, peaked at $73 million in 2021, and totaled $67.1 million in 2024. In 2023, NIH funding per annual deaths was $2765 for heart disease, $2724 for stroke, and $639 for VTE.

conclusionNIH investment in VTE research has increased over the past decade, but remains disproportionately low relative to other major causes of vascular mortality in the U.S.

Indexed as

Biomedical ResearchNational Institutes of Health (U.S.)Research Support as TopicVenous ThromboembolismHumansUnited StatesNational Institutes of Healthresearch fundingvenous thromboembolism

Identifiers

PMID41692096
PMCPMC12998937

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.