Evidence map›Paper›PMID 41691801›Full record

ArticleUltrasonics sonochemistry2026

Ultrasound-assisted and resin-based purification of bioactive polyphenols from peony (Paeonia ostii) pods: process optimization and α-glucosidase inhibitory activity.

Xiaoai Zhu, Yuan Ru, Kebing Yan, Siqi Zhang, Yingjie Sun, Fengke Du, Yage Liu, Yiying Niu, Jun Xi, Kunlun Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoai ZhuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China; Key Laboratory of Biology and Genetic Improvement of Oil Crops, Key Laboratory of Oilseeds Processing, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, PR China. Electronic address: zhuxiaoai@haut.edu.cn.
Yuan RuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Kebing YanFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Siqi ZhangFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Yingjie SunFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Fengke DuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Yage LiuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Yiying NiuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Jun XiFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
Kunlun LiuFood Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, PR China. Electronic address: lkl@haut.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The valorization of agricultural by-products into high-value ingredients requires efficient and green extraction technologies. Ultrasonic-assisted extraction (UAE) has emerged as a promising technique for this purpose due to its efficiency and environmental benefits. In this study, an integrated green process was developed for recovering bioactive polyphenols from peony (Paeonia ostii) pods (PPP), an underutilized by-product, using combined UAE and macroporous resin purification. The ultrasonication process was systematically optimized via response surface methodology. The determined optimal conditions (46 % ethanol, 14 mL/g liquid-solid ratio, 60 min ultrasonication) achieved a yield of PPP of 52.17 ± 0.06 mg GAE/g DW. Subsequent purification employing D101 macroporous resin and 40 % ethanol elution produced a refined polyphenol fraction, PPP40, with a purity of 43.93 %. Untargeted metabolomic profiling revealed 17 major phenolic constituents in PPP40, including gallic acid, kaempferol 7-O-glucoside, isorhamnetin-3-glucoside-4'-glucoside, and ethyl gallate as predominant compounds. The functional efficacy of the purified PPP40 fraction was evaluated based on its α-glucosidase inhibitory activity. PPP40 exhibited potent inhibition, with an IC

Indexed as

alpha-GlucosidasesChemical FractionationGlycoside Hydrolase InhibitorsPaeoniaPolyphenolsResins, SyntheticUltrasonic Wavesalpha-GlucosidasesGlycoside Hydrolase InhibitorsPolyphenolsResins, SyntheticBioactivityPeony podsPhenolic compoundsUltrasound-assisted extractionUPLC–MS/MS

Identifiers

PMID41691801
PMCPMC12925347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.