Evidence map›Paper›PMID 41690911›Full record

ArticleNature communications2026

Evolution of object identity information in sensorimotor cortex throughout grasp.

Yuke Yan, Anton R Sobinov, James M Goodman, Elizaveta V Okorokova, Lee E Miller, Sliman J Bensmaia

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A framework for quantifying the mechanics of dexterous grasp.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuke Yan *Committee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.
Anton R Sobinov *Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA. an.sobinov@gmail.com.ORCID http://orcid.org/0000-0003-0513-9194
James M GoodmanCommittee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.
Elizaveta V OkorokovaCommittee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.
Lee E MillerDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Sliman J BensmaiaCommittee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.

Funding

Sensory mechanisms of manual dexterity and their application to neuroprostheticsR35NS122333 · NINDS · UNIVERSITY OF CHICAGO · PI HATSOPOULOS, NICHOLAS G · 2021 to 2024
$4.5M
The interplay between kinematic and force representations in motor and somatosensory cortices during reaching, grasping, and object transportR01NS125270 · NINDS · UNIVERSITY OF CHICAGO · PI Jennifer L. Collinger, Robert A Gaunt · 2022 to 2026
$3.0M
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS125270U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R35NS122333
6 · The paper itself

Abstract

Reaching for and grasping an object seems a continuous process, yet somatosensory signals undergo dramatic state changes near the time of object contact. Tactile afferents start conveying contact forces, while on-going proprioceptive signals are altered as hand shape stops changing. How cortex maintains object identity in the presence of changing, multi-modal signals remains unknown. We quantified object-specific information in neurons of the primary motor cortex (M1) and somatosensory areas 3a, 3b/1, and 2 in male macaque monkeys. Surprisingly, despite the decrease in activity in each area immediately after contact, object identity information increased across sensorimotor cortex, particularly in purely cutaneous areas 3b/1, but also in multi-modal area 2. Uniquely among sensorimotor areas, object-specific information was present in M1 and 3a throughout grasp, although identity was encoded differently before and after contact. These shifts highlight the profound change in the complex coding of object identity in the sensorimotor cortex during grasp.

Indexed as

Hand StrengthMotor CortexSensorimotor CortexAnimalsMacaca mulattaMaleNeuronsSomatosensory Cortex

Identifiers

PMID41690911
PMCPMC13018631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.