Evidence map›Paper›PMID 41690521›Full record

ArticleAppetite2026

Longitudinal analysis of decision-making deficits in binge-eating disorders using drift diffusion modeling.

Glen Forester, Brianne N Richson, Erin E Reilly, Lisa M Anderson, Stephen A Wonderlich, Lauren M Schaefer

Abstract read
In one paragraph

Article in Appetite, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Glen ForesterCenter for Biobehavioral Research, Sanford Research, USA; Department of Psychiatry, University of North Dakota School of Medicine and Health Sciences, USA. Electronic address: forestergf@gmail.com.
Brianne N RichsonCenter for Biobehavioral Research, Sanford Research, USA; Department of Psychiatry, University of North Dakota School of Medicine and Health Sciences, USA.
Erin E ReillyDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, USA.
Lisa M AndersonDepartment of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, USA.
Stephen A WonderlichCenter for Biobehavioral Research, Sanford Research, USA; Department of Psychiatry, University of North Dakota School of Medicine and Health Sciences, USA.
Lauren M SchaeferCenter for Biobehavioral Research, Sanford Research, USA; Department of Psychiatry, University of North Dakota School of Medicine and Health Sciences, USA.

Funding

The Neurocognitive Reward Learning Mechanisms of Binge EatingP20GM134969 · NIGMS · SANFORD RESEARCH NORTH · PI BLACK, LORA · 2021 to 2025
$11.5M
Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
Using Computational Modeling to Test Reinforcement Learning as a Predictor of Response in Family-Based Treatment for Adolescent Anorexia NervosaK23MH131871 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erin E. Reilly · 2022 to 2026
$982k
Neural Bases of Disgust Conditioning in Anorexia NervosaK23MH123910 · NIMH · UNIVERSITY OF MINNESOTA · PI ANDERSON, LISA M · 2020 to 2024
$821k
NIGMS NIH HHS P20 GM134969NIMH NIH HHS K23 MH123910NIMH NIH HHS K23 MH131871NIMH NIH HHS T32 MH082761
6 · The paper itself

Abstract

Individuals with binge-type eating disorders (binge-EDs) repeatedly engage in binge eating despite negative consequences, suggesting altered decision-making. However, the specific cognitive mechanisms underlying these alterations remain poorly understood. In this longitudinal study, we applied the drift diffusion model (DDM) - a computational approach that isolates core decision-making components - to examine how these components relate to binge-eating frequency over time. Ninety-five adults with binge-EDs (69% binge-eating disorder; 15% bulimia nervosa) completed a probabilistic reward task at baseline and 3-month follow-up, with binge-eating frequency assessed concurrently and at 6-month follow-up. Results indicated that slower evidence accumulation (lower drift rate) consistently predicted greater binge-eating frequency both cross-sectionally (baseline p < .001; 3-month p = .018) and prospectively (6-month p < .001), highlighting impaired integration of decision-relevant information as a possible mechanism maintaining binge eating. A lower decision threshold, indicating less cautious decision-making, was cross-sectionally associated with greater binge-eating frequency (baseline p < .001) but did not predict symptoms over time (p-values >.552). In contrast, reward sensitivity (start bias) showed no significant relationship with binge-eating frequency (p-values >.357), possibly reflecting methodological limitations. These findings tentatively support the hypothesis that specific deficits in core decision-making processes contribute to binge-eating persistence, suggesting novel intervention targets. Additionally, our study demonstrates the utility of the DDM as a computational framework for unifying and interpreting diverse behavioral data within the binge-ED literature.

Indexed as

Binge-Eating DisorderDecision MakingAdultBulimiaBulimia NervosaCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleModels, PsychologicalProspective StudiesRewardYoung AdultBinge eatingDecision makingDrift diffusion modelEating disordersImpulsivity

Identifiers

PMID41690521
PMCPMC13041660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.