ArticleAnalytical and bioanalytical chemistry2026
Comprehensive pollutant screening in honey using integrated targeted and non-targeted LC-Q-Orbitrap HRMS.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents a comprehensive analytical framework combining targeted and non-targeted screening for pollutant residues in honey using liquid chromatography-quadrupole-Orbitrap high-resolution mass spectrometry (LC-Q-Orbitrap HRMS). A validated method targeting 30 veterinary drugs was extended to screen 300 honey samples. The analytical workflow employed Compound Discoverer software for data processing, integrating multiple database searches with stringent identification criteria including accurate mass (< 5 ppm), retention time (± 0.1 min), and MS2 fragmentation patterns. The screening identified 58 distinct compounds across diverse chemical classes. Pollutant residues included caffeine (69.7%), dulcin (61.7%), phenazone (41.0%), and multiple antibiotics, with sulfamethoxazole present in 20.0% of samples. Pesticide contamination was moderate, including acetamiprid (9.0%) and the neonicotinoid metabolite desnitro-imidacloprid (2.7%). Additionally, the non-targeted workflow captured 26 endogenous authenticity markers spanning flavonoids, phenolic acids, amino acids, organic acids, and sugar markers. Notably, aflatoxin B1 was detected in 2.7% of samples, alongside various mycotoxins and natural products. The wide concentration ranges observed, spanning 3-4 orders of magnitude, suggest both point-source and background environmental contamination. This integrated targeted/non-targeted approach demonstrates honey's utility as a biomonitoring matrix while revealing extensive contamination that warrants enhanced regulatory oversight.
Indexed as
Identifiers
41689661What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.