Evidence map›Paper›PMID 41689592›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Magnetoencephalography changes in cervical spondylotic myelopathy: a study of resting-state and somatosensory evoked magnetic fields.

Geng Zhao, Zhuang Miao, Lianlei Wang, Junyuan Sun, Tianyu Gao, Fulong Wang, Shiqiang Zheng, Xu Zhang, Xinyu Liu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

9 authors.

Geng Zhao *School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Zhuang Miao *School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Lianlei WangDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Junyuan SunDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Tianyu GaoSchool of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Fulong WangSchool of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Shiqiang ZhengSchool of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Xu ZhangSchool of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China. zhang_xu@buaa.edu.cn.
Xinyu LiuDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, China. newyuliu@163.com.

Funding

2022 Industrial Technology Basic Public Service Platform Project 2022-189-181Innovation Program for Quantum Science and Technology 2021ZD0300503Key R&D Program of Shandong Province, China 2022ZLGX03National Key R&D Program of China 2023YFC2509700
6 · The paper itself

Abstract

objectiveThis study aimed to assess the diagnostic utility of optically pumped magnetometer-based magnetoencephalography (OPM-MEG) in patients with cervical spondylotic myelopathy (CSM).

methodsA total of 31 CSM patients and 32 healthy volunteers were enrolled. Somatosensory-evoked magnetic fields (SEFs) were recorded using OPM-MEG. Clinical evaluations included the Japanese Orthopaedic Association (JOA) scale and the Short Form-36 (SF-36) health survey. Diagnostic performance was evaluated using receiver operating characteristic (ROC) analysis.

resultsCompared with healthy controls, CSM patients demonstrated decreased α power in the occipital region, and increased γ power in the occipital, temporal, and frontal regions. Significant differences in phase locking value (PLV) were observed in the α band between the occipital-frontal regions. The latency of the maximum SEF was 49.66 ± 5.51 ms in healthy controls and 58.63 ± 7.73 ms in CSM patients. ROC analysis for SEF latency yielded an area under the curve of 0.844, with a cutoff value of 55.0 ms, sensitivity of 77.4%, and specificity of 81.3%.

conclusionMEG may a helpful tool in the functional assessment of the neurological deficits in CSM, and shows potential as an useful method for clinical diagnosis and functional evaluation of this condition.

Indexed as

Cervical VertebraeEvoked Potentials, SomatosensoryMagnetoencephalographySpinal Cord DiseasesSpondylosisAdultAgedFemaleHumansMaleMiddle AgedROC CurveCervical spondylotic myelopathyMagnetoencephalographyPhase locking valuePower spectral densitySomatosensory-evoked magnetic field

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.