ArticleJACC. Case reports2026
Strategic Reintervention With Marked Oversizing and Overexpansion in TAV-in-SAV for Hemolytic Paravalvular Leak.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
backgroundParavalvular leak (PVL) is a common complication of surgical aortic valve replacement and may recur even after transcatheter plug closure. CASE SUMMARY: A 71-year-old man developed recurrent PVL with hemolytic anemia 4 years after plug closure after redo surgical aortic valve replacement with a 25-mm Carpentier-Edwards Perimount Magna Ease valve. Valve-in-valve transcatheter aortic valve replacement was performed using a 29-mm Sapien 3 Ultra Resilia valve (Edwards Lifesciences). To achieve sufficient oversizing and annular apposition, a deliberately oversized valve was selected and deployed using balloon overfilling. DISCUSSION: We report the intentional use of an oversized Sapien 3 valve with deliberate overexpansion beyond the standard size recommended for a 25-mm Magna Ease valve. This strategy led to effective PVL sealing and the complete resolution of hemolysis. TAKE-HOME MESSAGES: Anatomy-guided valve oversizing, combined with intentional overexpansion, is pivotal to procedural success. This approach may be a viable treatment option for high-risk patients with recurrent PVL.
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