Evidence map›Paper›PMID 41689453›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026

Detecting Fibromuscular Dysplasia-Related Renal Artery Stenosis: CTA or Doppler US?

Fuzhou Yi, Zhifang Yang, Zhe Zhang, Yifei Yu, Xiaofeng Ni, Yunyun Hu, Xiaoyu Li, Yuanyuan Kang, Jianzhong Xu, Ri Ji

Abstract readComparative Study
PubMed Full text at PMC Publisher
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Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Fuzhou YiDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0009-0002-2966-5906
Zhifang YangDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhe ZhangDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yifei YuDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaofeng NiDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yunyun HuDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoyu LiDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuanyuan KangDepartment of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-9121-5872
Jianzhong XuDepartment of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ri JiDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the diagnostic efficacy of Doppler ultrasound (DUS) and computed tomography angiography (CTA) in patients with renal artery fibromuscular dysplasia (FMD)-related severe renal artery stenosis (RAS).

methodsIn this retrospective study, 78 patients with hypertension were confirmed FMD-related severe RAS based on clinical and angiographical features. All participants underwent standardized renal DUS and CTA. Two blinded readers independently classified lesions and assessed hemodynamics, with discrepancies resolved by a third senior radiologist. Diagnostic performance of DUS and CTA was compared per segment and overall using digital subtraction angiography (DSA) as the reference standard.

resultsA total of 157 renal arteries were analyzed, 86 of which demonstrated severe stenosis accompanied with abnormal arteriographic features of FMD. Integrated analysis showed higher sensitivity for DUS versus CTA in detecting FMD-related severe stenoses (overall: 97.7% versus 67.4%, p < .001; main renal arteries: 98.5% versus 79.4%, p = .001; accessory/branch arteries: 94.4% versus 22.2%, Δ72.2%, p < .001). Both modalities achieved 100% specificity for accessory/branch lesions. DUS demonstrated 100% specificity for main artery lesions and overall, whereas CTA was 97.7% for main artery lesions and 97.2% overall.

conclusionDUS outperformed CTA for FMD-related severe RAS, especially with consistent accuracy across vascular territories, supporting its potential as a preferred imaging modality in FMD evaluation.

Indexed as

Computed Tomography AngiographyFibromuscular DysplasiaRenal Artery ObstructionUltrasonography, DopplerAdultAgedFemaleHumansMaleMiddle AgedRenal ArteryReproducibility of ResultsRetrospective StudiesSensitivity and Specificitycomputed tomography angiographyDoppler ultrasoundfibromuscular dysplasiasevere renal artery stenosis

Identifiers

PMID41689453
PMCPMC13356425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.