Evidence map›Paper›PMID 41689245›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2026

Estimating the economic burden of diabetes in young adults: A global analysis based on the GBD 2021 and a value of statistical life year framework.

Hang Guo, Zhaoyu Guo, Yunfei Liu, Quan Zhang

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Article in Diabetic medicine : a journal of the British Diabetic Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hang GuoNHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China.ORCID https://orcid.org/0000-0001-8712-9787
Zhaoyu GuoBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Yunfei LiuDepartment of Mechanical Engineering, Tsinghua University, Beijing, China.
Quan ZhangOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-3626-4855

Funding

China Postdoctoral Science Foundation 2024M762380FEDER within the scope of COMPETE 2030National Funds via FCT COMPETE2030-FEDER-00698600National Funds via FCT MPr-2023-12-SACCCT-Projetos de IC&DTNational Funds via FCT UIDP/04539/2020National Natural Science Foundation of China 82305007
6 · The paper itself

Abstract

aimsThe rising prevalence of diabetes in young adults threatens global health and sustainable development. However, its full macroeconomic impact, especially the welfare losses beyond conventional productivity costs, has not been systematically quantified at a global level. We aimed to estimate the current and future global economic burden of diabetes in individuals aged 15-39 years using a welfare-based approach.

methodsUsing disability-adjusted life-years (DALYs) from the Global Burden of Disease Study 2021, we monetized health losses into a value of lost welfare (VLW) via a value of a statistical life year approach. We estimated the VLW globally, regionally and nationally, analysed its distribution by Socio-Demographic Index (SDI) and made projections to 2050.

resultsIn 2021, the global economic burden was Int$1.16 trillion. Low-SDI regions had the highest relative burden (1.21% of GDP), whereas high-SDI regions had the largest absolute loss. Geographically, East Asia showed the highest absolute burden (Int$240.30 billion) and Oceania the highest relative impact (3.03% of GDP). Projections show the burden will more than double by 2050 to 1.32% of global GDP, driven almost entirely by type 2 diabetes.

conclusionsDiabetes in young adults represents a significant and growing macroeconomic burden. Our findings underscore the urgent need for public health strategies and economic policies focused on preventing type 2 diabetes. Such interventions are especially critical for countries with fragile health systems to mitigate substantial future economic and health losses.

Indexed as

Cost of IllnessDiabetes MellitusDisability-Adjusted Life YearsGlobal Burden of DiseaseGlobal HealthAdolescentAdultFemaleHumansMalePrevalenceQuality-Adjusted Life YearsYoung Adultdiabetesdisability‐adjusted life yearsglobal healthhealth economics

Identifiers

PMID41689245
PMCPMC12982657

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.