Evidence map›Paper›PMID 41688964›Full record

ArticleBMC complementary medicine and therapies2026

The potential effects of traditional Chinese medicine on the outcomes after breast cancer surgery: a large population-based study.

Chao-Tsung Chen, Ta-Liang Chen, Chuen-Chau Chang, Pei-Ying Wu, Yi-Sheng Chou, Chun-Chieh Yeh, Chung-Hua Hsu, Chien-Chang Liao

Abstract read
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Article in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chao-Tsung ChenInstitute of Traditional Medicine, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Ta-Liang ChenDepartment of Anesthesiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Chuen-Chau ChangDepartment of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Pei-Ying WuDepartment of Traditional Chinese Medicine, China Medical University Hsinchu Hospital, Hsinchu, Taiwan.
Yi-Sheng ChouDepartment of Hematology and Oncology, Taipei City Hospital, Renai Branch, Taipei, Taiwan.
Chun-Chieh YehDepartment of Surgery, China Medical University Hospital, Taichung, Taiwan.
Chung-Hua HsuInstitute of Traditional Medicine, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Chien-Chang LiaoDepartment of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. ccliao@tmu.edu.tw.

Funding

National Science and Technology Council NSTC112-2314-B-038-141
6 · The paper itself

Abstract

backgroundDetailed evidence concerning the impact of traditional Chinese medicine (TCM) on clinical outcomes for breast cancer patients in Taiwan is not yet fully available. Our research sought to examine the association between TCM integration and postoperative outcomes among women undergoing mastectomies.

methodsUtilizing a large insurance database, we identified a cohort of adult women who underwent breast cancer surgery during the 2010–2019 period. We compared sociodemographic profiles and comorbidities between TCM users and non-users. Multiple logistic regression models were employed to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for both mortality and postoperative complications.

resultsAmong 91,298 eligible patients, the one-year preoperative prevalence of TCM utilization was 39.8%. Compared to the control group, TCM users demonstrated a significantly lower likelihood of postoperative stroke (OR 0.76, 95% CI 0.62–0.93) and a reduced requirement for intensive care (OR 0.74, 95% CI 0.59–0.91). Notably, a cumulative exposure of more than four TCM consultations within the year preceding surgery was specifically linked to a decreased risk of stroke (OR 0.76, 95% CI 0.61–0.95).

conclusionTCM utilization is prevalent among the Taiwanese breast cancer population prior to surgery. Our findings suggest that preoperative TCM use is correlated with improved post-mastectomy outcomes, particularly regarding stroke prevention and reduced intensive care needs. Nevertheless, these observational benefits warrant further confirmation through prospective and large-scale clinical investigations.

Indexed as

Breast NeoplasmsMastectomyMedicine, Chinese TraditionalPostoperative ComplicationsAdultAgedFemaleHumansMiddle AgedTaiwanBeneficial effectBreast cancer, MastectomySurgeryTraditional Chinese medicineUtilizationWomen

Identifiers

PMID41688964
PMCPMC13005486

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