ArticleBMC geriatrics2026
Long-term outcomes in elderly colorectal cancer patients with presarcopenia: a single center retrospective cohort study.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsufficient evidence exists regarding the characteristics of elderly patients with presarcopenia and their prognosis. Therefore, we aim to investigate the impact of preoperative presarcopenia on postoperative outcomes in elderly patients with resectable colorectal cancer.
methodsWe included patients aged ≥ 75 years who underwent curative resection between June 2009 and December 2019. The psoas muscle index was calculated based on the computed tomography scan at the L3 level (lumbar area). The primary outcome was the difference in overall survival based on the presence or absence of presarcopenia. The secondary outcomes included differences in the occurrence of postoperative complications, tumor recurrence, and the impact of adjuvant chemotherapy on survival rates in high-risk stage II cancer.
resultsWe included 325 patients (presarcopenia: 63) in this study. The presarcopenia group was older than the normal group (p = 0.02), with a lower body mass index (p < 0.001). Preoperative blood test results indicated a higher frequency of anemia (p = 0.002), hypoalbuminemia (p = 0.009), and a higher neutrophil-to-lymphocyte ratio (p = 0.012) in the presarcopenia group. Postoperative complications did not differ significantly between the two groups (p = 0.989). In multivariate analysis, presarcopenia emerged as a significant factor affecting overall survival (HR 1.75, 95% CI 1.15–2.67, p = 0.009), but not recurrence-free survival (HR 1.48, 95% CI 0.86–2.55, p = 0.156). Presarcopenia in high-risk stage II colorectal cancer appeared to be a factor where adjuvant chemotherapy did not influence overall survival (HR 1.70, 95% CI 0.40 – 7.26, p = 0.475).
conclusionIn patients with poor overall survival associated with presarcopenia, adjuvant chemotherapy should be selectively considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.