ArticleScientific reports2026
Bioactivity screening of endophytic fungi from Sterculia urens and GC-MS metabolites profiling of the potent isolate Chaetomium meridiolense.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endophytic fungi associated with medicinal plants are recognized as promising sources of bioactive secondary metabolites. In this study, fungal endophytes were isolated from healthy leaves of Sterculia urens, an ethnomedicinal plant with documented therapeutic relevance, and evaluated for their phytochemical composition and biological activities. Nine endophytic fungi were screened for antioxidant potential using DPPH and ABTS radical scavenging assays and for antibacterial activity against Staphylococcus aureus, Escherichia coli, and Salmonella typhi through minimum inhibitory and bactericidal concentration analyses. Among the isolates, Chaetomium meridiolense exhibited comparatively higher antioxidant and antibacterial activities and was therefore selected for detailed metabolic investigation. This isolate also showed elevated phenolic and flavonoid contents, suggesting a chemical basis for its bioactivity. Gas chromatography-mass spectrometry analysis revealed a metabolite profile enriched with terpenoid- and phenolic-derived compounds. Multivariate statistical analyses indicated positive associations between phenolic enrichment and observed antioxidant and antibacterial effects. Overall, this study provides new insight into the bioactive potential of C. meridiolense associated with S. urens and supports the relevance of endophytic fungi as potential sources of biologically active metabolites for further exploration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.