ArticleApplied microbiology and biotechnology2026
Molecular breeding alters mycelium material properties in the white-rot fungus Pleurotus ostreatus.
Article in Applied microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycelium-based materials derived from white-rot fungi have attracted increasing attention as sustainable and eco-friendly alternatives to conventional products. However, their mechanical strength and durability remain relatively inferior. Molecular breeding of white-rot fungi offers a promising strategy to address these limitations. Recent studies have suggested that mycelial density and cell wall structure play key roles in determining the physical properties of mycelium-based materials. In this study, we disrupted mbp1, which encodes a transcription factor required for normal mycelial growth and cell wall synthesis, in the white-rot fungus Pleurotus ostreatus and investigated the effects on mycelium mats and mycelium-based composites. The mycelium mats of the dikaryotic mbp1 disruptants exhibited higher Young's moduli and ultimate tensile strengths than those of the control strain (20b×#61), indicating that mbp1 disruption resulted in stiffer mycelium mats. This may be because of the increased mycelial density in the dikaryotic mbp1 disruptants. In addition, the dikaryotic mbp1 disruptants produced harder mycelium-based composites than the strain 20b×#61. These findings indicate that mbp1 disruption improved the characteristics of mycelium-based composites. To our knowledge, this is the first study demonstrating that molecular breeding can enhance the performance of mycelium-based composites, thereby paving the way for the development of efficient strategies to advance mycelium-based materials. KEY POINTS: • mbp1 disruption resulted in stiffer mycelium mats. • Dikaryotic mbp1 disruptants formed thinner but denser mycelium mats. • mbp1 disruption improved the mechanical strength of mycelium-based composites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.