Evidence map›Paper›PMID 41688479›Full record

ArticleScientific data2026

Near telomere-to-telomere diploid genome assembly of Acrossocheilus wenchowensis.

Lingzhan Xue, Mingkun Luo, Haoyu Wang, Wenbin Zhu, Duhuang Chen, Gaoxiong Zeng, Mengxiang Liao, Ji Zhao, Bin Wu, Luohao Xu and 1 more

Abstract readDataset
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lingzhan Xue *Freshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China.
Mingkun Luo *Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Freshwater Fisheries Research Center of Chinese Academy of Fishery Sciences,, Ministry of Agriculture and Rural Affairs, Wuxi, Jiangsu, China.ORCID http://orcid.org/0000-0003-3885-9155
Haoyu Wang *Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, MOE Key Laboratory of Freshwater Fish Reproduction and Development, School of Life Sciences, Southwest University, Chongqing, 400715, China.
Wenbin ZhuKey Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Freshwater Fisheries Research Center of Chinese Academy of Fishery Sciences,, Ministry of Agriculture and Rural Affairs, Wuxi, Jiangsu, China.
Duhuang ChenFreshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China.
Gaoxiong ZengFreshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China.
Mengxiang LiaoFreshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China.
Ji ZhaoFreshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China.
Bin WuFreshwater Fisheries Research Institute of Fujian Province, Fuzhou, Fujian, China. wubinfire@126.com.
Luohao XuIntegrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, MOE Key Laboratory of Freshwater Fish Reproduction and Development, School of Life Sciences, Southwest University, Chongqing, 400715, China. luohaox@gmail.com.ORCID http://orcid.org/0000-0002-3714-8047
Zaijie DongKey Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Freshwater Fisheries Research Center of Chinese Academy of Fishery Sciences,, Ministry of Agriculture and Rural Affairs, Wuxi, Jiangsu, China. dongzj@ffrc.cn.ORCID http://orcid.org/0000-0001-5428-1053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrossocheilus wenchowensis is a lukewarm-water fish found in southern Chinese mountain streams, valued for both ornamental and edible purposes. We assembled a near telomere-to-telomere (T2T) genome using HiFi, ONT, Hi-C and Illumina data. The assembly is approximately 870.69 Mb with a contig N50 of about 21.28 Mb. Among these, 14 chromosomes in Hap1 and 15 chromosomes in Hap2 have reached T2T levels. A total of 24,909 protein-coding genes were predicted in Hap1 and 24,496 in Hap2, with BUSCO scores of 97.4% and 97.6%, respectively. A conserved centromeric satellite sequence (262 bp) derived from an LTR transposon was identified. Comparative genomics showed that Acrossocheilus and Onychostoma diverged approximately 13.7 million years ago (Mya), while A. wenchowensis diverged from A. fasciatus about 5.25 Mya. Resequencing of four geographic populations of A. wenchowensis revealed distinct genetic structure in the LY group compared to the other populations based on SNP and InDel analysis. This genome provides a framework for diploid T2T studies in fish and supports further functional genomics research.

Indexed as

CyprinidaeGenomeTelomereAnimalsDiploidy

Identifiers

PMID41688479
PMCPMC13018573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.