Evidence map›Paper›PMID 41688416›Full record

ReviewJournal of cellular and molecular medicine2026

Emerging Regulatory Mechanisms in Sinoatrial Node Automaticity.

Hongyu Liu, Yuting Cao, Xuling Su

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Emerging Regulatory Mechanisms in Sinoatrial Node Automaticity.Journal of cellular and molecular medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongyu LiuDepartment of Pathology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuting CaoDepartment of Laboratory Diagnostics, Third Affiliated Hospital of Naval Medical University (Eastern Hepatobiliary Surgery Hospital), Shanghai, China.
Xuling SuDepartment of Pathology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-3754-9457

Funding

National Natural Science Foundation of China 82400388National Natural Science Foundation of China 82500335Shanghai Sixth People's Hospital Basic Research Project, Youth Cultivation Fund yuqn202320Shanghai Sixth People's Hospital Basic Research Project, Youth Cultivation Fund yuqn202417
6 · The paper itself

Abstract

The sinoatrial node (SAN), the primary cardiac pacemaker, governs rhythmic heartbeats through spontaneous electrical impulses. While the classical "coupled-clock" theory, integrating the membrane voltage clock (driven by cyclic ion channel activity) and the calcium clock (orchestrated by rhythmic sarcoplasmic reticulum Ca

Indexed as

Sinoatrial NodeAnimalsBiological ClocksCalciumHumansReactive Oxygen SpeciesSignal TransductionCalciumReactive Oxygen Speciescoupled‐clock theoryglutamatergic signallingmolecular modulatorspacemaker cell microenvironmentsinoatrial node automaticity

Identifiers

PMID41688416
PMCPMC12904774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.