Evidence map›Paper›PMID 41687344›Full record

ArticleInternational dental journal2026

Effect of Pre-Orthodontic CGF-Assisted GTR for Class II Furcation Lesions After Orthodontic Treatment: 5-Year Observation.

Jing Qiao, Lingyan Peng, Xinying Wang, Yong Zhang, Jinyu Duan, Na An, Xiangying Ouyang

Abstract read
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In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing QiaoDepartment of Periodontology, the First Clinical Division, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China. Electronic address: donaldshushu@aliyun.com.
Lingyan PengDepartment of Periodontology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.
Xinying WangDepartment of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.
Yong ZhangDepartment of Periodontology, the First Clinical Division, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.
Jinyu DuanDepartment of Periodontology, the First Clinical Division, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.
Na AnDepartment of General Dentistry II, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China. Electronic address: anna@pkuss.bjmu.edu.cn.
Xiangying OuyangDepartment of Periodontology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China. Electronic address: kqouyangxy@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe purpose of this case series is to discuss the effect of orthodontic treatment (OT) on the regenerative surgery of furcation defects. MATERIAL AND

methodsThis was a consecutive case series with a 5-year follow-up. Eight patients of stage III periodontitis with 10 mandibular Class II buccal furcation defects were included. The furcation defects were treated by guided tissue regeneration combined with bone graft and concentrated growth factors. OT was started at 1-year post-surgery. Clinical examination and CBCT were performed at baseline, 12 months post-surgery, and 5 years post-surgery.

resultsThe mean clinical attachment loss and probing depth improved from baseline to different time points post-surgery. And there were no significant changes at subsequent time points post-surgery (P > .05). A statistically significant reduction in the mean horizontal, vertical bone loss, and volume of furcation defects from baseline to different time points post-surgery has been shown (P < .001). No statistically significant difference was observed between 1-year and 5 years post-surgery (P > .05).

conclusionsIn summary, the combined regenerative therapy showed good results in the treatment of furcation defects. Moreover, the combined regenerative therapy was shown to be maintained throughout and following orthodontic treatment.

Indexed as

Furcation DefectsGuided Tissue Regeneration, PeriodontalOrthodontics, CorrectiveBone TransplantationCone-Beam Computed TomographyFemaleFollow-Up StudiesHumansMaleTreatment OutcomeBone graftConcentrated growth factorsFurcationOrthodontic therapyPeriodontal regeneration

Identifiers

PMID41687344
PMCPMC12925051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.