Evidence map›Paper›PMID 41687100›Full record

ArticleJMIR formative research2026

Real-World Use of a Mental Health AI Companion: Multiple Methods Study.

Christine Callahan, Leah Tanner, Chelsea Coe, Michelle Davis, Jenna Glover, Ellis Bernstein, Katherine Scranton, Kenli Urruty, Matthew Chester, Sarah Kunkle

Abstract read
In one paragraph

Article in JMIR formative research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine CallahanHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0002-3729-6672
Leah TannerHeadspace, Inc., San Francisco, CA, United States.ORCID 0009-0001-0440-7700
Chelsea CoeHeadspace, Inc., San Francisco, CA, United States.ORCID 0009-0003-8775-2642
Michelle DavisHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0002-8162-5541
Jenna GloverHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0002-9042-0820
Ellis BernsteinHeadspace, Inc., San Francisco, CA, United States.ORCID 0009-0002-6044-401X
Katherine ScrantonHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0002-7656-676X
Kenli UrrutyHeadspace, Inc., San Francisco, CA, United States.ORCID 0009-0009-4667-2260
Matthew ChesterHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0001-9397-2949
Sarah KunkleHeadspace, Inc., San Francisco, CA, United States.ORCID 0000-0002-6368-0205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rapid acceleration of large language models (LLMs) creates opportunities to expand the accessibility of mental health support; however, general artificial intelligence (AI) tools lack safety guardrails, evidence-based practices, and medical regulation compliance, which may result in misinformation and failing to escalate care in crises. In contrast, Ebb, Headspace's conversational AI tool (CAI tool), was purpose-built by clinical psychologists and research experts using motivational interviewing techniques for subclinical guidance, incorporating clinically backed safety mechanisms.

objectiveThis study aimed to (1) understand Headspace members' sentiment toward AI and expectations for a mental health CAI tool, (2) evaluate real-world use of Headspace's CAI tool, and (3) understand how members perceive a CAI tool fitting into their mental health journey.

methodsThis was a multiple method study using three data sources including Headspace members: (1) cross-sectional survey (n=482) assessing demographics, AI use, and the Artificial Intelligence Attitude Scale-4 (AIAS-4); (2) real-world engagement descriptive analysis (n=393,969) assessing session and message counts, retention, and conversation themes; and (3) diary study (n=15) exploring the CAI tool's role within members' mental health journey. App engagement was compared between CAI tool 1.0 and CAI tool 2.0, where CAI tool 2.0 featured enhanced LLM conversational prompts, comprehensive memory, woven content recommendations, and more robust safety detection.

resultsWhile the majority of survey respondents used and would continue to use general AI tools, overall attitudes toward AI remained neutral (AIAS-4 mean 5.7, SD 2.2, range 1-10). Survey results suggest that members viewed the CAI tool as a guide to navigate to mental health resources and Headspace content and provide in-the-moment support. Members emphasized the need for data safety and ethics transparency, clinical guidelines structure, and for the CAI tool to be a resource in addition to human-delivered mental health care, not a replacement. Real-world CAI tool use showed strong engagement across 393,969 Headspace members. The product evolution to CAI tool 2.0 led to increased retention (77,894/153,249, 50.8% completed 2 sessions within 7 days vs 68,701/240,720, 28.5% for CAI tool 1.0) and higher positive conversation ratings (37,819/40,449, 93.5% vs 94,308/104,323, 90.4%). Retained CAI tool 2.0 users showed greater retention (6.1 sessions per user) compared to all CAI tool 2.0 users (2.9 sessions per user) and CAI tool 1.0 (2.4 sessions per user). Diary study results suggest that members imagined using the CAI tool when feeling stress or anxiety and during morning routines, commutes, or while winding down at night.

conclusionsResults emphasize the necessity of research-backed, purpose-built mental health AI products with minimum viable safeguards, including (1) transparent labeling of intended use, benefits, and limitations; (2) safety by design principles to monitor for overuse, detect risk, and flag needs for escalation; and (3) child and adolescent safeguards.

Indexed as

Artificial IntelligenceMental HealthAdultCross-Sectional StudiesFemaleHumansLarge Language ModelsMaleMiddle AgedSurveys and QuestionnairesAIartificial intelligencedigital mental healthHeadspacemental healthmental health chatbot

Identifiers

PMID41687100
PMCPMC12949398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.