Evidence map›Paper›PMID 41686784›Full record

ArticlePloS one2026

Determinants of underweight and overweight/obesity among people with tuberculosis in Kampala, Uganda: A cross-sectional study.

Simon Kyazze, Saidi Appeli, Joseph Baruch Baluku, Jonathan Izudi

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simon KyazzeInstitute of Public Health and Management, Clarke International University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-7682-2516
Saidi AppeliDepartment of Agribusiness and Extension, Faculty of Agriculture and Animal Sciences, Busitema University, Soroti, Uganda.ORCID https://orcid.org/0000-0002-7661-2236
Joseph Baruch BalukuDivision of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5852-9674
Jonathan IzudiInstitute of Public Health and Management, Clarke International University, Kampala, Uganda.ORCID https://orcid.org/0000-0001-9065-0389

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition significantly contributes to mortality among people with tuberculosis (TB). However, evidence on factors associated with the specific forms of malnutrition, specifically underweight and overweight/obesity, beyond clinical determinants, remains limited in many settings. We investigated the prevalence and determinants of underweight and overweight/obesity among people with pulmonary TB across five health facilities in Kampala, Uganda.

methodsThis analytic cross-sectional study involved people with pulmonary TB, either clinically diagnosed or bacteriologically confirmed, aged ≥18 years sampled across five health facilities in Kampala, Uganda. Nutritional status was assessed using body mass index (BMI, kg/m²) and categorized as underweight (<18.5), normal weight (18.5-24.9), and overweight/obese (≥25.0). To identify factors independently associated with nutritional status, normal weight was considered as the reference category in a multinomial logistic regression analysis, adjusting for multiple covariates and clustering at the health facility level. The measure of association was the adjusted relative risk ratios (aRRR) and the corresponding 95% confidence intervals (CI).

resultsOf the 818 participants studied, 417 (51.0%) had normal weight, 302 (36.9%) were underweight, and 99 (12.1%) were overweight or obese. Adjusted analysis showed that being underweight was associated with household food insecurity (aRRR 2.04, 95% CI: 1.48-2.80) while being overweight or obese was associated with self-employment (aRRR 2.26, 95% CI: 1.35-3.79) and being newly diagnosed with TB (aRRR 2.10, 95% CI: 1.30-3.41).

conclusionThis study, conducted among people with pulmonary TB in an urban setting in Uganda, showed that underweight and overweight/obesity are prevalent. Furthermore, the study showed that food insecurity is associated with being underweight, while being overweight or obese is associated with being self-employed or newly diagnosed with TB. Therefore, TB control programs need to regularly assess the nutritional status of people with TB to mitigate the effect of being underweight or overweight on treatment outcomes.

Indexed as

ObesityOverweightThinnessTuberculosis, PulmonaryAdolescentAdultBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutritional StatusPrevalenceRisk FactorsUganda

Identifiers

PMID41686784
PMCPMC12904450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.