SynthesisMedicine2026
Incidence risk and risk factors for postcholecystectomy syndrome: A systematic review and meta-analysis.
Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Post-Cholecystectomy nutritional management: a comprehensive review of evidence-based guidelines and clinical practice.Frontiers in surgery · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostcholecystectomy syndrome (PCS) is a clinically significant condition with a variable reported occurrence. This study was conducted to quantitatively synthesize the overall incidence of PCS through meta-analysis and identify its associated risk factors.
methodsA comprehensive literature search was conducted across multiple databases, including China National Knowledge Infrastructure, Wanfang, Chinese Technical Sciences Periodical Database (VIP), China Biology Medicine, PubMed, Cochrane Library, Embase, and Web of Science, from inception to April 2025. Cohort and case-control studies investigating the incidence and risk factors of PCS following cholecystectomy were included. Statistical analysis was performed using RevMan 5.4 software.
resultsNine studies involving 2948 cholecystectomy patients were included in the meta-analysis. The pooled analysis demonstrated that the overall incidence of PCS was 3.21% (95% confidence interval: 2.27-4.55%). Preoperative complications were identified as a strong risk factor for PCS (OR = 26.91, 95% confidence interval: 7.87-92.03, P < .00001).
conclusionPCS presents a considerable clinical risk, particularly in patients with preexisting symptoms. Clinicians should prioritize preoperative assessment, with special attention to symptomatic patients, and implement individualized perioperative management strategies to mitigate PCS risk.
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