Evidence map›Paper›PMID 41686538›Full record

ArticleUnited European gastroenterology journal2026

Bloating, Visible Abdominal Distension, and Other Intestinal Gas-Related Symptoms in Irritable Bowel Syndrome and Functional Dyspepsia.

Tom van Gils, Ryo Katsumata, Jóhann P Hreinsson, Douglas A Drossman, Jan Tack, Hans Törnblom, Boris Le Nevé, Laurent Quinquis, Rim Hassouna, Max J Schmulson and 3 more

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. UEG Journal-In Times of Turmoil, Science Matters.United European gastroenterology journal · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tom van GilsDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0009-0006-2103-9491
Ryo KatsumataDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jóhann P HreinssonDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Douglas A DrossmanUniversity of North Carolina/Chapel Hill, Chapel Hill, North Carolina, USA.
Jan TackDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hans TörnblomDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-2117-9874
Boris Le NevéDanone Research & Innovation, Gif-sur-Yvette, France.
Laurent QuinquisDanone Research & Innovation, Gif-sur-Yvette, France.
Rim HassounaDanone Research & Innovation, Gif-sur-Yvette, France.
Max J SchmulsonLaboratory of Neurogastroenterological Disorders, Unit of Experimental Medicine Dr Ruy Pérez Tamayo (UME), Faculty of Medicine, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Shrikant I BangdiwalaDepartment of Health Research Methods, Evidence and Impact, and, Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Olafur S PalssonUniversity of North Carolina/Chapel Hill, Chapel Hill, North Carolina, USA.
Magnus SimrénDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

ALF-agreement ALFGBG-965173Danone Nutricia ResearchErling-Persson FoundationFaculty of Medicine, University of GothenburgSwedish Research Council 2021-00947
6 · The paper itself

Abstract

backgroundBloating refers to the sensation of tension in the abdomen, reported in the presence or absence of visible abdominal distension. These and other gas-related symptoms are often reported by patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). However, the prevalence of bloating and visible abdominal distension as separate symptoms in these disorders is not well known. The aim of this study was to investigate the link between bloating, distension, and intestinal gas-related symptoms with IBS and FD, and their overall impact.

methodsData from a population-based internet survey of adults from the US, UK, and Mexico were used. This survey included Rome IV diagnostic questions for IBS and FD, questions to distinguish between ≥ weekly bloating and/or distension, and the Intestinal Gas Questionnaire (IGQ) to assess the impact of six gas-related symptoms.

resultsThe analyses included 131 individuals with only IBS, 360 with only FD, 217 with IBS + FD and 4740 without IBS and FD (reference group). Individuals with IBS (64.9%), FD (50.6%), and especially IBS + FD (88.5%) reported bloating and/or distension more frequently than the reference group (13.7%). Bloating and distension as distinct and combined symptoms were strongly linked to IBS and FD even after correcting for confounding factors. Also, other gas-related symptoms had a higher impact on individuals with IBS and/or FD compared with the reference group. DISCUSSION: Bloating and visible abdominal distension can occur as concomitant or distinct impactful symptoms and are, together with other gas-related symptoms, strongly linked to IBS and FD. These findings may provide arguments to include bloating and distension as supportive criteria for IBS and FD diagnoses.

Indexed as

DyspepsiaFlatulenceIrritable Bowel SyndromeAdultFemaleGasesHumansMaleMexicoMiddle AgedPrevalenceSurveys and QuestionnairesSymptom BurdenUnited KingdomUnited StatesYoung AdultGasesabdominal distensionbloatingfunctional dyspepsiagas‐related symptomsirritable bowel syndrome

Identifiers

PMID41686538
PMCPMC12904287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.