Evidence map›Paper›PMID 41686342›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Intensive nursing interventions for post-treatment anxiety and depression in bladder cancer: A systematic review and meta-analysis.

Xianzhi Huang, Ruoxi Chen, Zihang Guo, Conghua Song, Xiaomei Li

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Intensive nursing intervention: what is the post treatment effect size on anxiety and depression?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Xianzhi HuangSchool of Basic Medicine, Putian University, No. 1133 Xueyuan Middle Street, No. 450 Dongzhen West Road, Chengxiang District, Putian, 351100, Fujian Province, China.
Ruoxi ChenSchool of Basic Medicine, Putian University, No. 1133 Xueyuan Middle Street, No. 450 Dongzhen West Road, Chengxiang District, Putian, 351100, Fujian Province, China.
Zihang GuoSchool of Basic Medicine, Putian University, No. 1133 Xueyuan Middle Street, No. 450 Dongzhen West Road, Chengxiang District, Putian, 351100, Fujian Province, China.
Conghua SongGastrointestinal Endoscopy Center, The Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Licheng District, Putian, 351100, Fujian Province, China. kesongs@email.ncu.edu.cn.ORCID http://orcid.org/0000-0002-1908-0640
Xiaomei LiSchool of Basic Medicine, Putian University, No. 1133 Xueyuan Middle Street, No. 450 Dongzhen West Road, Chengxiang District, Putian, 351100, Fujian Province, China. xmlee0104@163.com.ORCID http://orcid.org/0000-0002-0349-2392

Funding

National Natural Science Foundation of China 82200676The Collaborative Project Between the Hospital and College of Putian University 2024106The Fujian Provincial Health Technology Project 2024GGA089The Science and Technology Planning Projects of Putian of Fujian Province 2023SZ3001PTXY01
6 · The paper itself

Abstract

BACKGROUND &

aimsPost-treatment anxiety and depression are prevalent but often underrecognized among bladder cancer patients. This systematic review and meta-analysis aimed to estimate the pooled prevalence of these symptoms and to evaluate the effectiveness of intensive nursing interventions.

methodsA comprehensive search of PubMed, EMBASE, the Cochrane Library, and Web of Science was conducted through October 18, 2025. Eligible studies included those reporting the prevalence or severity of anxiety and/or depression in bladder cancer patients, as well as studies comparing intensive nursing interventions with routine care. Data were synthesized using Stata/MP version 14.0. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed using the I

resultsSixteen studies involving 1,791 patients were included. The pooled prevalence of anxiety was 25.3% (95% CI: 22.2-28.6%) and that of depression was 29.4% (95% CI: 23.3-35.9%). Higher prevalence rates were observed in non-Western populations and among patients receiving multimodal treatment. Compared with routine care, intensive nursing interventions were associated with significant reductions in anxiety (SMD = -4.52; 95% CI: -6.07 to -2.96) and depression (SMD = -4.51; 95% CI: -5.96 to -3.07) (both P < 0.001). These findings remained robust in sensitivity analyses despite substantial heterogeneity.

conclusionAnxiety and depression are common among bladder cancer survivors. Intensive nursing interventions are associated with meaningful improvements in psychological outcomes and may be considered for integration into post-treatment supportive care.

trial registrationPROSPERO registration number: CRD42024590858.

Indexed as

AnxietyDepressionUrinary Bladder NeoplasmsHumansPrevalenceAnxietyBladder cancerDepressionMeta-analysisNursing interventionPsychological care

Identifiers

PMID41686342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.