Evidence map›Paper›PMID 41686312›Full record

ArticleHistochemistry and cell biology2026

The yeast peroxisomal proteome at absolute quantitative scale.

Hirak Das, Silke Oeljeklaus, Renate Maier, Julian Bender, Bettina Warscheid

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Histochemistry and cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hirak Das *Biochemistry II, Theodor-Boveri-Institute, Faculty of Chemistry and Pharmacy, University of Würzburg, Am Hubland, 97094, Würzburg, Germany.ORCID http://orcid.org/0009-0009-6060-1557
Silke Oeljeklaus *Biochemistry II, Theodor-Boveri-Institute, Faculty of Chemistry and Pharmacy, University of Würzburg, Am Hubland, 97094, Würzburg, Germany.ORCID http://orcid.org/0000-0001-8908-4295
Renate MaierBiochemistry II, Theodor-Boveri-Institute, Faculty of Chemistry and Pharmacy, University of Würzburg, Am Hubland, 97094, Würzburg, Germany.
Julian BenderBiochemistry II, Theodor-Boveri-Institute, Faculty of Chemistry and Pharmacy, University of Würzburg, Am Hubland, 97094, Würzburg, Germany.ORCID http://orcid.org/0000-0003-3316-9999
Bettina WarscheidBiochemistry II, Theodor-Boveri-Institute, Faculty of Chemistry and Pharmacy, University of Würzburg, Am Hubland, 97094, Würzburg, Germany. bettina.warscheid@uni-wuerzburg.de.ORCID http://orcid.org/0000-0001-5096-1975

Funding

Deutsche Forschungsgemeinschaft 278002225/RTG 2202European Union's Horizon 2020 research 812968
6 · The paper itself

Abstract

Peroxisomes are dynamic organelles vital for lipid metabolism and redox homeostasis. In Saccharomyces cerevisiae, the expression of peroxisomal proteins is tightly regulated in response to metabolic conditions. Here, we provide the first absolute quantification of the yeast peroxisomal proteome under peroxisome-inducing (oleate) and fermentative (glucose) conditions using a label-free mass spectrometry approach. We determined protein copy numbers for ~ 4500 proteins, including 99 peroxisomal and peroxisome-associated proteins. Our data reveal that the overall peroxisomal proteome is approximately threefold more abundant in oleate-grown cells, constituting 2.8% (2.01 × 10

Indexed as

PeroxisomesProteomeSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsOleic AcidOleic AcidProteomeSaccharomyces cerevisiae ProteinsAbsolute quantificationMass spectrometryPeroxisomesProtein copy numbersProteomic rulerSaccharomyces cerevisiae

Identifiers

PMID41686312
PMCPMC12904895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.