Evidence map›Paper›PMID 41686230›Full record

ReviewVirchows Archiv : an international journal of pathology2026

Plasma cells and plasmacytoid features in thyroid lesions.

Qianqian Zhang, Angela Feraco, Belen Padial Urtueta, Elisabetta Merenda, Luisa Cioni, Alessia Piermattei, Patrizia Straccia, Federica Cianfrini, Antonino Mule, Liron Pantanowitz and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qianqian ZhangDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Angela FeracoDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Belen Padial UrtuetaDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Elisabetta MerendaDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Luisa CioniDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Alessia PiermatteiDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Patrizia StracciaDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Federica CianfriniDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Antonino MuleDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Liron PantanowitzDepartment of Pathology, University of Pittsburg, Pittsburg, PA, USA.
Esther Diana RossiDivision of Anatomic Pathology and Histology-Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy. esther.rossi@policlinicogemelli.it.ORCID http://orcid.org/0000-0003-3819-4229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most thyroid lesions are of epithelial origin characterized by a papillary and/or follicular pattern. However, lesions involving plasma cells or plasmacytoid cytomorphology that mimic plasma cells can rarely be encountered in the thyroid gland. Thyroid lesions involving true plasma cells include benign entities such as chronic lymphocytic thyroiditis and neoplasms including plasmacytoma. Thyroid lesions that present with plasmacytoid features include medullary thyroid carcinoma. Rendering the correct diagnosis may be difficult due to the rarity of these lesions, overlapping cytomorphologic features, and challenges selecting the appropriate ancillary studies. This review discusses those thyroid entities showing plasmacytoid cell features and emphasizes their relevance to the recent Bethesda system for reporting thyroid cytopathology and WHO classification of endocrine tumors.

Indexed as

Fine needle aspiration cytologyImmunocytochemistryPersonalized medicinePlasma cellsPlasmacytoid thyroid lesionsThyroid malignancies

Identifiers

PMID41686230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.