ArticleJournal of bacteriology2026
Genetic evidence for a periplasmic protein as a third component for a subset of NtrYX family two-component systems.
Alexa R Wolber, Liliana S McKay, Richard M Johnson, Zain T Hameed, Katlyn B Mote, Steven M Julio, Peggy A Cotter
Abstract read
In one paragraphArticle in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors.
Alexa R Wolber *Department of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0009-0003-7775-8039 Liliana S McKay *Department of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0001-5426-5539 Richard M JohnsonDepartment of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Zain T HameedDepartment of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Katlyn B MoteDepartment of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Steven M JulioDepartment of Biology, Westmont College, Santa Barbara, California, USA.
Peggy A CotterDepartment of Microbiology and Immunology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-3726-3990 Funding
Cooperative roles of FHA and ACT in Bordetella virulenceR01AI153160 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COTTER, PEGGY A · 2021 to 2025
$2.6MPlrSR-dependent Signal Transduction in Bordetella VirulenceR01AI129541 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COTTER, PEGGY A · 2017 to 2021
$2.5MIdentifying the Bordetella PlrSR regulonR21AI177818 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOURRET, ROBERT B., COTTER, PEGGY A · 2023 to 2024
$432kNIH HHS R01 AI129541NIH HHS R01 AI153160NIH HHS R21 AI177818
6 · The paper itselfAbstract
PlrSR, a member of the NtrYX family of two-component regulatory systems (TCSs), is required for the classical bordetellae, including the causative agent of whooping cough, IMPORTANCE:
Indexed as
Bacterial ProteinsBordetella pertussisPeriplasmic ProteinsGene Expression Regulation, BacterialMultigene FamilyOperonPromoter Regions, GeneticBacterial ProteinsPeriplasmic ProteinsBordetellagene regulationNtrYXproteobacteriatwo-component regulatory system
Identifiers
PMID41685908
PMCPMC13001219
What OpenQuestion holds
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