Trial reportEuropean endodontic journal2025
Outcomes of Direct Pulp Capping After Carious Excavation of Deep Caries on Permanent Mature Teeth: An Ancillary Study Derived From A Randomised Clinical Trial.
Trial report in European endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Regenerative Potential of Biodentine in Complex Endodontic Conditions: A Systematic Review of Clinical and Radiological Evidence.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Clinical Outcomes of Immediate and Delayed Composite Restorations After Pulp Capping with Biodentine: A Systematic Literature Review.Journal of functional biomaterials · 2026Review
- Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the clinical efficacy of direct pulp capping (DPC) using Biodentine���, a calcium silicate-based cement, in cases of carious pulp exposure, focusing on pulp survival and treatment success.
methodsThis study retrospectively included all patients with pulp exposure who participated in the randomised clinical trial. Follow-up was performed at 1, 2 and 3 years after treatment. The primary outcome was pulp survival. The secondary outcomes were patient satisfaction, marginal integrity of the restoration, and overall survival (defined as both pulp survival and marginal integrity success combined). To account for censoring, pulp survival, marginal integrity success, and overall survival were analysed using the actuarial survival methods.
resultsOf the 36 patients included, the pulp survival, marginal integrity success, and overall survival rates at one year (95% confidence interval (CI)) were 0.912 (0.816-1.000), 0.971 (0.914-1.000) and, 0.882 (0.774-0.991), respectively. At two years, the conditional pulp survival and overall survival rates were both 0.926 (0.827-1.000) and the marginal integrity rate was 1 (1-1). After three years, the conditional pulp survival rate, marginal integrity rate and overall survival rate were 0.953 (0.864-1.000), 0.907 (0.784-1.000) and 0.86 (0.714-1.000), respectively. From the patients' view, the restorations were considered clinically satisfactory, with only one patient expressing concerns after two years.
conclusionsDespite the potential for attrition bias, our results are promising and consistent with the existing literature. This study supports DPC as a reliable therapeutic approach for managing pulp exposure following carious excavation.(EEJ-2025-01-015).
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