Evidence map›Paper›PMID 41685347›Full record

ReviewJSES reviews, reports, and techniques2026

Outcomes of reverse total shoulder arthroplasty vs. other surgical fixation methods for proximal humerus fractures in elderly patients.

Julie Mekhail, Ryan Mullan, James L Cross, Om Jahagirdar, Xuan Luo, Motasem Salameh

Abstract readReview
In one paragraph

Review in JSES reviews, reports, and techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julie MekhailDepartment of Orthopaedics and Rehabilitation, Yale University, New Haven, CT, USA.
Ryan MullanDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
James L CrossDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Om JahagirdarDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Xuan LuoDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Motasem SalamehDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Proximal humerus fractures (PHFs) are among the most common osteoporotic injuries in elderly patients, typically resulting from low-energy mechanisms such as ground-level falls. Multiple surgical options exist, including reverse total shoulder arthroplasty (rTSA), open reduction and internal fixation (ORIF), and hemiarthroplasty (HA), but the optimal treatment remains debated. This up-to-date systematic review and meta-analysis aimed to evaluate the comparative effectiveness of rTSA, HA, and ORIF for treating PHFs in the geriatric population. Methods: A systematic review and meta-analysis were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed (MEDLINE), EMBASE, and Web of Science were searched through January 2025. Eligible studies included randomized controlled trials or cohort studies comparing rTSA with HA and/or ORIF in patients aged ≥ 65 years. Two reviewers independently screened studies using predefined inclusion criteria. The primary outcome was postoperative functional scores; secondary outcomes included: complication rates, revision surgery rates, shoulder range of motion, and quality of life metrics. Results: Twenty studies met the inclusion criteria. rTSA demonstrated significantly better Constant-Murley Scores (standardized mean difference [SMD] = 0.67, Conclusion: rTSA offers superior functional outcomes and complication rates compared to HA and a more favorable revision profile than ORIF in elderly patients with PHFs. These findings support the growing preference for rTSA as the primary surgical treatment in this population, though further high-quality, long-term studies are needed to guide individualized decision-making.

Indexed as

ComplicationsElderlyHemiarthroplastyOpen reduction internal fixationOutcome measuresProximal humerus fractureReverse total shoulder arthroplastyrTSA

Identifiers

PMID41685347
PMCPMC12890702

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.