Evidence map›Paper›PMID 41685282›Full record

ArticleAfrican journal of thoracic and critical care medicine2025

An evaluation of spirometric reference equations for detecting obstructive airway disease in South African children: A cohort study.

T L Mkhize, L B Zurba, R Masekela

Abstract read
In one paragraph

Article in African journal of thoracic and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T L MkhizeDepartment of Paediatrics and Child Health, College of Health Sciences, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.
L B ZurbaEducation for Health Africa, Durban, South Africa.
R MasekelaDepartment of Paediatrics and Child Health, College of Health Sciences, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0001-9665-2035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurate diagnosis of obstructive lung disease in paediatric populations depends on the use of spirometry reference equations that reflect the regional and ethnic diversity of the population studied. Objectives: To evaluate the diagnostic variability between the Global Lung Initiative 2012 (GLI Methods: This retrospective cohort study analysed spirometry data from 171 children, aged 6 - 18 years, attending a paediatric pulmonology clinic in Durban, SA, from January 2012 to December 2021. Key spirometry parameters (forced expiratory volume in 1 second (FEV Results: Comparison of spirometry outcomes using the GLI Conclusion: This study underscores the diagnostic variability that arises from using global spirometry reference equations in a multi-ethnic paediatric population, particularly in SA. Future studies should include a more diverse ethnic representation to enhance data relevance. Study synopsis:

Indexed as

ethnicitylung functionobstructive airway diseasepaediatricreference equationsSpirometry

Identifiers

PMID41685282
PMCPMC12892202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.