ArticleAnnals of neurosciences2026
Examining Negative Emotional Reactivity and State Self-esteem as Mediators of the Relationship Between Core Self-evaluation and Depressive Symptoms.
Article in Annals of neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The World Health Organization (WHO) has recognised depression as one of the leading causes of illness and disability across the world. Young adults are highly susceptible to depression, as this age group stands at a critical junction of developmental transitions and increased psychosocial demands. Existing research indicates the importance of dispositional factors like self-evaluation mechanisms in relation to depression, but little attention has been paid to contextual factors like self-esteem and emotional reactivity and how the dispositional and contextual factors interact with each other to produce the risk of depression in young adults. Purpose: The study aims to investigate core self-evaluation (CSE), state self-esteem (SSE) and negative emotional reactivity (ER-N) as predictors of depressive symptoms. Additionally, it aims to assess the role of SSE and ER-N as mediators in the relationship between CSE and depressive symptoms. Methods: 438 participants between 18 and 25 years of age were assessed. The strength and direction of the relationships among CSE, SSE, ER-N and depressive symptoms were examined by the Pearson correlation coefficient. Furthermore, a mediation analysis was run to assess the role of negative emotion regulation (ER-N) and self-esteem in the relationship between CSE (independent variable) and depressive symptoms (dependent variable). Results: A positive association was found between CSE and SSE, while on the other hand CSE and SSE both were negatively correlated with ER-N and depressive symptoms. This is despite the fact that ER-N significantly associates positively with depressive symptoms. Further, higher CSE exhibits fewer depressive symptoms, both directly and indirectly. Among SSE and ER-N as mediators, SSC emerged as a stronger mediator in the relationship. Conclusion: Overall, the study highlights that positive CSE is likely to promote self-esteem in contextual situations and is also likely to manage emotional reactivity of a negative nature. The findings indicate that higher CSE reduces depression primarily by strengthening self-esteem and minimising negative emotional reactivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.