ArticleFrontiers in endocrinology2026
Standardizing cervical lymph node evaluation in papillary thyroid carcinoma: diagnostic accuracy of Node-RADS on ultrasound.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Prognostic significance of the extent of extranodal extension in patients with pN1b papillary thyroid carcinoma: a retrospective cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To assess the diagnostic performance of the Node Reporting and Data System (Node-RADS) in ultrasonographic evaluation of cervical lymph node (LN) metastasis in papillary thyroid carcinoma (PTC) and compare it with conventional suspicious sonographic features. Materials and methods: This retrospective study included 227 PTC patients (269 LNs) who underwent preoperative cervical LN ultrasound and biopsy (September 2022-December 2023). Two radiologists independently assigned Node-RADS scores (1-5) based on LN size and morphologic features (shape, border, echogenicity). Diagnostic performance was evaluated using ROC analysis, with histopathology as the reference standard. Node-RADS was compared to five American Thyroid Association (ATA)-defined suspicious features (microcalcifications, cystic changes, etc.). Multivariable analysis assessed an integrated model combining Node-RADS with peripheral vascularity. Results: Metastatic LNs (63.9%, 172/269) exhibited higher Node-RADS scores (malignancy rates: 35.7% for score 1 vs. 88.2% for score 5). Node-RADS achieved an AUC of 0.720 (95% CI: 0.662-0.773), surpassing individual features (best AUC: 0.703 for peripheral vascularity). Inter-reader agreement was good ( Conclusions: Node-RADS offers standardized, reproducible risk stratification for cervical LN metastasis in PTC, with moderate diagnostic accuracy. Integration with peripheral vascularity enhances performance, supporting its potential clinical utility in preoperative assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.