Evidence map›Paper›PMID 41685142›Full record

ArticleActa pharmaceutica Sinica. B2026

Blocking TRIM47-mediated HNF4

Huanyu Hong, Mengchao Xiao, Hui Qian, Siqi Tan, Sihan Wu, Fang Liu, Xialu Hong, Shuqing Liu, Chenhong Ding, Keqi Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Huanyu HongDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Mengchao XiaoDepartment of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Hui QianDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Siqi TanDepartment of Gastroenterology, Jiangnan University Medical Center (Wuxi No.2 People's Hospital), Wuxi 214002, China.
Sihan WuDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Fang LiuDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Xialu HongDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Shuqing LiuDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Chenhong DingDepartment of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Keqi WangDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Weifen XieDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Xin ZhangDepartment of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have highlighted the downregulation of hepatocyte nuclear factor 4alpha (HNF4

Indexed as

CZ-2401Hepatocellular carcinomaHNF4αProtein–protein interactionsSmall moleculeTRIM47UbiquitinationVirtual screening

Identifiers

PMID41685142
PMCPMC12891897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.