Evidence map›Paper›PMID 41684920›Full record

SynthesisFrontiers in medicine2026

Bibliometric and visual analysis of gut microbiota research in functional bowel disorders from 2016 to 2025.

Yujie Su, Xin Su, Zhengtao Chen, Lexun Wang, Jia Chen

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yujie SuSchool of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Xin SuSchool of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Zhengtao ChenSchool of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Lexun WangInstitute of Chinese Medicine (Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine), Guangdong Pharmaceutical University, Guangzhou, China.
Jia ChenSchool of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Research into Functional bowel disorders (FBDs) is increasingly focused on the role of gut microbiota (GM) in their pathogenesis and treatment. Nevertheless, a thorough and organized assessment of the existing research landscape remains absent. This study aimed to assess the research landscape, hotspots, and clinical advancements concerning GM in FBDs from 2016 to 2025, thereby providing a theoretical reference for future investigations. Methods: Publications from 2016 to 2025 were sourced from the Web of Science Core Collection and Scopus databases. These datasets were analyzed through a comprehensive bibliometric approach using R software, VOSviewer, and CiteSpace, with the resulting data visually represented for clearer interpretation. In addition, we collected clinical trials from PubMed during this period to evaluate advancements in the field. Results: From 2016 to 2025, the field of GM in FBDs exhibited a substantial overall increase in annual publications, with China being the most prolific contributor, followed by the United States, Italy, the United Kingdom, and Australia. The United States maintains the most extensive international collaboration network. At the institutional level, Mayo Clinic in the United States and University College Cork in Ireland emerged as the most active hubs for cooperative research. The journal Conclusion: This study employed bibliometric and visual analytic approaches to provide a systematic overview of the research landscape and to identify key hotspots in GM research related to FBDs, offering critical insights that may guide future scientific investigations and clinical applications.

Indexed as

bibliometricfunctional bowel disordersgut-brain axisgut microbiotahotspotstrends

Identifiers

PMID41684920
PMCPMC12891093

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.