ArticleSovremennye tekhnologii v meditsine2025
Production of Platelet-Rich Gel Using Allogeneic Platelets Isolated from Donor Whole Blood.
Article in Sovremennye tekhnologii v meditsine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Materials and Methods: The study investigated donor blood platelets, platelets collected from donors via apheresis, and platelets isolated from donor whole blood (platelet-leukocyte concentrates, PLC). Platelet quality was assessed before and after centrifugation at 2500-4000 g, as well as the feasibility of producing platelet gel from platelet-rich plasma isolated from whole blood. Morphofunctional analysis of platelets was performed using an original method based on the examination of vitally stained cells by fluorescence microscopy. The cytokine profile in the platelet concentrates isolated from whole blood was evaluated using multiplex analysis. Results: Following centrifugation at 2500-4000 g, the platelet population exhibited an increased number of platelets with damaged membranes, procoagulant platelets, and platelets prone to spontaneous activation. Centrifugation at 2500-2700 g was less damaging than centrifugation at 2701-4000 g and allowed to preserve a significant volume of growth factors within the platelets. Platelet-rich plasma isolated from PLC can be used to produce platelet gel and thrombofibrin clot Conclusion: There was developed a method for producing platelet gel and a thrombofibrin clot at 20-22°C based on allogeneic platelets isolated from donor whole blood. These materials can be used as wound dressings, applicative biological constructs for treating tissue defects of various origins, and in the creation of composite biological designs intended for use in regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.