ArticleSpartan medical research journal2025
Comparing Clinical Treatments and Outcomes of Patients with Atrial Fibrillation and Obstructive Sleep Apnea.
Article in Spartan medical research journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Advancing Clinical Insight, Medical Education, and Global Health: A Synthesis of Evidence-Based Research and Interdisciplinary Innovation.Spartan medical research journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAtrial fibrillation (AF) is a common arrhythmia that is bidirectionally associated with obstructive sleep apnea (OSA), where OSA increases the risk of AF onset and recurrence, while AF may exacerbate OSA symptoms through hemodynamic and autonomic mechanisms. Both conditions pose significant global public health concerns and increase cardiovascular risk. However, the effect of OSA on AF management strategy and outcome has not been explored previously. The purpose of our study was to evaluate clinical outcomes in patients with AF and OSA.
methodsOur study included 130 patients over the age of 18 with AF, of which 100 patients were diagnosed with OSA. We evaluated multiple clinical outcomes including comorbidities, treatment strategies, vitals, end organ function, and mortality from June, 2021 to November, 2023 through retrospective chart review. Data was analyzed using chi-square, fisher's exact test and logistic regression.
resultsResults were significant for a predominance in rate control management strategy (12% rhythm control vs 75% rate control) used in AF with OSA and predominance in rhythm control management strategy (88.9% rhythm control vs 3.7% rate control) used in AF without OSA (p=0.0279). Evaluating mortality in patients with both AF and OSA, COPD (54.6% mortality) and CHF (78.8%) were associated with significantly higher mortality (p<0.0001). There was no significant mortality benefit between rate versus rhythm strategy overall in any patient with AF (OR 0.49, CI 0.153-1.570, p-value =0.229).
conclusionsWhile rate and rhythm control strategies are used interchangeably in managing AF, our study emphasizes a role of OSA in determining rate versus rhythm management strategy for AF treatment. Thus, the presence or absence of underlying OSA may be used as a clinical decision-making factor in managing AF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.