ReviewFrontiers in nutrition2026
From mechanisms to management: a comprehensive review of sarcopenia in gastric cancer.
Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unimodal to Multimodal Prehabilitation in Gastric Cancer Surgery: Systematic Review of Randomised Controlled Trials.Journal of gastrointestinal cancer · 2026Pooled it
- Mechanotransduction Failure and Molecular Rescue in Gastric Cancer: Kinetotherapy Across the IL-6/STAT3-Myostatin/ACVR2B-Akt/mTOR Axis.Medical sciences (Basel, Switzerland) · 2026Review
- Precision nutrition in gastric cancer: current advances and future directions.Frontiers in nutrition · 2026Review
- Sarcopenia in breast cancer: prognostic values and emerging therapeutic strategies.Frontiers in surgery · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric cancer (GC), a leading cause of global cancer mortality, induces systemic changes impacting patient prognosis. A growing body of evidence shows a significantly increased prevalence of sarcopenia in GC patients, closely linked to poor outcomes such as higher postoperative complications, enhanced chemotherapy toxicity, and shortened survival. However, its underlying mechanisms and optimal management remain not fully clarified. This review comprehensively analyzes the pathological mechanisms and clinical significance of GC-related sarcopenia, emphasizing systemic inflammation, metabolic/nutritional disorders, neuroendocrine dysfunction, and anti-tumor therapy impacts. Additionally, feasible management methods such as nutritional support, exercise intervention, and related drug treatment were also proposed. By synthesizing current evidence, we delineate sarcopenia's integral role in GC and propose pragmatic strategies to ultimately improve patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.