Evidence map›Paper›PMID 41684701›Full record

ArticleNational science review2026

Horizontal gene transfer and gene loss drove the divergent evolution of host dependency in Micrarchaeota.

Yang-Zhi Rao, Yu-Xian Li, Ze-Wei Li, Yan-Ni Qu, Brian P Hedlund, Tom A Williams, Yan-Ling Qi, Qi-Jun Xie, Hai-Long Yang, Yuan-Qi Zhang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Divergent evolution of the PRPS enzymes across the tree of life.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yang-Zhi RaoState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0002-3895-2301
Yu-Xian LiState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Ze-Wei LiState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Yan-Ni QuState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Brian P HedlundSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Tom A WilliamsDepartment of Life Sciences, University of Bath, Bath BA2 7AX, UK.ORCID https://orcid.org/0000-0003-1072-0223
Yan-Ling QiState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Qi-Jun XieState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Hai-Long YangState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Yuan-Qi ZhangState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Hong-Chen JiangGeomicrobiology Laboratory, State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China.ORCID https://orcid.org/0000-0003-1271-7028
Marike PalmerDepartment of Microbiology, University of Manitoba, Manitoba R3T 2N2, Canada.
Mang ShiCentre for Infection and Immunity Study (CIIS), School of Medicine (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.ORCID https://orcid.org/0000-0002-6154-4437
Wen-Sheng ShuSchool of Life Sciences, South China Normal University, Guangzhou 510275, China.
Zheng-Shuang HuaState Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.ORCID https://orcid.org/0000-0002-2405-4228
Wen-Jun LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0002-4237-6140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The DPANN superphylum is a deep-branching radiation of archaea with small cell and genome sizes. Most DPANN lineages are predicted or validated to be host-dependent. However, certain lineages have substantial biosynthetic capacities and are potentially less dependent on hosts, or even free-living. Here, we reconstructed 163 Micrarchaeota genomes, comprising 48 assigned to previously undescribed orders and 115 affiliated with known orders. Investigation of their genetic repertoire revealed substantial metabolic capacity in Norongarragalinales-, Anstonellales- and the newly proposed Wunengiarchaeales-associated lineages, including complete or near-complete glycolysis and

Indexed as

DPANNevolutionary historyhorizontal gene transfermetabolic capacityreductive evolution

Identifiers

PMID41684701
PMCPMC12892359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.