ArticleArchives of medical science : AMS2025
Allicin suppressed bladder cancer cell biological activities via regulation of the miR-26b-5p/PTEN axis in an
Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Exploring the role of natural bioactive molecules in genitourinary cancers: how far has research progressed?Natural products and bioprospecting · 2023Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The aim of this study was to investigate the anti-tumour effects of allicin in bladder cancer and to elucidate the related mechanisms by performing an Material and methods: Using the 5637 and T24 cell lines as model systems, the cell proliferation, apoptosis, cell invasion number and wound-healing rate were measured by MTT, flow cytometry, and Transwell and wound-healing assays. The expression of miR-26b-5p mRNA was evaluated by qRT-PCR assay, and relative protein expression (PTEN, PI3K and AKT) was evaluated by western blot assay. The correlation between miR-26b-5p and PTEN in 5637 and T24 cells was examined by the Dual Luciferase assay. Results: Compared with the normal control (NC) group, cell proliferation was significantly depressed as apoptosis increased ( Conclusions: Allicin has anti-tumour effects on bladder cancer cell biological activities, and the mechanism may involve regulation of the miR-26b-5p/PTEN axis in bladder cancer cells.
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