Evidence map›Paper›PMID 41684527›Full record

ReviewFrontiers in psychiatry2025

Effects of prenatal psychotherapies and psychosocial interventions on depressive symptoms, anxious symptoms and stress: a systematic review and network meta-analysis.

Lanting Huo, Xingfeng Yu, Yujia Ma, Lei Yang, Xiaomei Li

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lanting HuoFaculty of Nursing, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xingfeng YuThe Nursing Department, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Yujia MaDepartment of Nursing, Chinese People's Liberation Army General Hospital, Beijing, China.
Lei YangFaculty of Nursing, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xiaomei LiFaculty of Nursing, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Perinatal psychological disorders have a significant impact on maternal and neonatal health. While many psychotherapies and psychosocial interventions have been developed and empirically evaluated for the management of perinatal psychological symptoms, the efficacy of these interventions and the most effective intervention modality remain inconclusive. Aim: To assess and compare the efficacy of various perinatal psychotherapies and psychosocial interventions for depressive symptoms, anxious symptoms and stress through a comprehensive systematic review with network meta-analysis. Methods: Eleven English and Chinese electronic databases were searched from inception to 30 November 2024. The Revised Cochrane Risk of Bias tool for randomized trials was used to assess the quality of the evidence. Standard pairwise meta-analyses were conducted for direct comparisons using Review Manager 5.3, and network meta-analyses were performed using Stata 16 and ADDIS 1.16.5 for different types of interventions based on random-effects models. Design: Systematic review and network meta-analysis with qualitative and quantitative syntheses were performed to holistically investigate intervention effectiveness. Results: A total of 85 randomized controlled trials were included in the analysis, 65 of which provided available data for quantitative synthesis. The synthesized results suggest that prenatal psychotherapies and psychosocial interventions tend to be effective in reducing depressive symptoms, anxious symptoms and stress with standardized mean differences (SMDs) of -0.70, -0.81, and -1.05, respectively. Multicomponent interventions (SMD=-1.14), interpersonal psychotherapy (SMD=-0.75), cognitive behavioral therapy (SMD=-0.69), mindfulness-based interventions (SMD=-0.68), and psychoeducation (SMD=-0.14) significantly decreased depression symptoms. Acceptance and commitment therapy (SMD=-1.66), interpersonal psychotherapy (SMD=-1.24), counseling (SMD= -1.13), multicomponent interventions (SMD=-0.86), mindfulness-based interventions (SMD=-0.84), and cognitive behavioral therapy (SMD=-0.81) were effective in alleviating anxiety symptoms. Multicomponent interventions (SMD=-5.74), mindfulness-based interventions (SMD=-1.31), cognitive behavioral therapy (SMD=-1.03), and counseling (SMD=-0.82) appeared to be effective strategies for the management of perinatal stress. Conclusions: Prenatal psychotherapies and psychosocial interventions are effective in reducing depressive symptoms, anxious symptoms and stress. Specifically, multicomponent interventions, counseling, and mindfulness-based interventions are superior for alleviating the symptoms of depressive symptoms, anxious symptoms and stress, respectively. Cognitive behavioral therapy may be a reasonable option that could produce a beneficial effect on all of these prenatal psychological problems.

Indexed as

network meta-analysisperinatal anxious symptomsperinatal depressive symptomsperinatal stresspsychotherapies and psychosocial interventionssystematic review

Identifiers

PMID41684527
PMCPMC12890675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.