Evidence map›Paper›PMID 41684441›Full record

ArticleImaging neuroscience (Cambridge, Mass.)

Cortical activity for conversational responses in young neurotypical individuals, older neurotypical individuals, and individuals with aphasia: A functional near-infrared spectroscopy study.

Emily J Braun, Erin A Carpenter, Yuanyuan Gao, Meryem A Yücel, David A Boas, Swathi Kiran

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily J BraunBoston University Center for Brain Recovery, Boston, MA, United States.ORCID https://orcid.org/0000-0003-4687-8516
Erin A CarpenterBoston University Center for Brain Recovery, Boston, MA, United States.ORCID https://orcid.org/0000-0002-7958-6803
Yuanyuan GaoBoston University Neurophotonics Center, Boston, MA, United States.
Meryem A YücelBoston University Center for Brain Recovery, Boston, MA, United States.
David A BoasBoston University Center for Brain Recovery, Boston, MA, United States.ORCID https://orcid.org/0000-0002-6709-7711
Swathi KiranBoston University Center for Brain Recovery, Boston, MA, United States.ORCID https://orcid.org/0000-0003-1586-8913

Funding

The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain functionU01EB029856 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI BOAS, DAVID A, KIRAN, SWATHI · 2020 to 2024
$6.5M
NIBIB NIH HHS U01 EB029856
6 · The paper itself

Abstract

Functional near-infrared spectroscopy (fNIRS) has the potential for evaluating language and conversational interaction in an ecologically valid way given that participants can be seated and interacting with a conversational partner. Aphasia, an acquired language disorder, impacts language abilities, including conversational interaction. Understanding of cortical activity in people with aphasia for conversational tasks could provide an ecologically valid index of brain function and recovery patterns in this population. This study provides pilot data in the use of fNIRS to evaluate language production for conversational responses in young (adult) neurotypical individuals, adults with post-stroke aphasia, and age-matched (i.e., older) neurotypical adults. Experiment 1 evaluated cortical activity for conversational responses versus sentence repetition in a computer-based conversational question task. Experiment 1 results showed differentiation between experimental conditions (with greater fronto-temporoparietal cortical activity for question answering vs. repetition) in young healthy individuals that was not seen in the people with aphasia and age-matched individuals. Experiment 2 evaluated cortical activity for conversational responses in a structured conversational question task with a live interlocutor versus sentence repetition. Experiment 2 results showed lower cortical activity across regions of interest in the age-matched group and greater cortical activity for question answering versus repetition in bilateral temporal and left parietal regions of interest in the people with aphasia. This study provides preliminary evidence for the potential of fNIRS to characterize cortical activity after stroke for functional language tasks.

Indexed as

aphasiafNIRSfunctional near-infrared spectroscopylanguageneuroimaging

Identifiers

PMID41684441
PMCPMC12892348

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.