ArticleThe American journal of case reports2026
Endovascular Stenting for Malignant Superior Vena Cava Syndrome Complicated by Interstitial Pneumonia: A Report of 2 Cases.
Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND Superior vena cava syndrome (SVCS) is a clinical condition most commonly caused by malignancy. Its management becomes challenging when complicated by interstitial pneumonia because radiotherapy carries a high risk of fatal adverse events. This report presents 2 cases of malignant SVCS complicated by interstitial pneumonia that were successfully managed with endovascular superior vena cava (SVC) stenting. CASE REPORT Case 1: A 68-year-old man with advanced small-cell lung cancer was admitted due to facial and bilateral upper-limb edema. He was diagnosed with SVCS caused by tumor compression based on contrast-enhanced computed tomography (CT). With a prognosis of surviving only a few months, and radiation therapy deemed difficult due to interstitial pneumonia, SVC stent placement was performed. After the procedure, the edema improved and he was discharged after 7 days. Case 2: A 75-year-old man with pulmonary squamous cell carcinoma was admitted due to facial and bilateral upper-limb edema, and dyspnea. A diagnosis of SVCS caused by tumor compression was established using contrast-enhanced CT. Based on a prognosis of surviving several months and interstitial pneumonia as a contraindication for radiation therapy, SVC stent placement was performed. The edema improved after the procedure and he was discharged 7 days later. CONCLUSIONS Stenting can be a useful indication for malignant SVCS, even in cases complicated by interstitial pneumonia. SVC stenting offers a fast and safe treatment option, quickly improving symptoms and quality of life, and allowing for early patient discharge.
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