Evidence map›Paper›PMID 41684065›Full record

ArticleHead & neck2026

How Would You Treat? A Case-Vignette Study of Provider Treatment Preferences in Human Papillomavirus-Mediated Oropharyngeal Cancer.

Sindhura Sridhar, Michael R Papazian, Michael C Topf

Abstract read
In one paragraph

Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sindhura SridharDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0009-0009-3649-3920
Michael R PapazianDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-0630-4940
Michael C TopfDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-1022-4417

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
Augmented Reality to Guide Head and Neck Cancer SurgeryK08CA293255 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Michael Topf · 2024 to 2026
$645k
NCI NIH HHS 1K08CA293255-0NCI NIH HHS K08 CA293255NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

backgroundCurrent guidelines recommend surgical resection, definitive radiotherapy (RT), or concurrent chemoradiotherapy (CRT) for human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). This study aimed to provide insight into practice patterns of providers who treat HPV-associated OPSCC.

methodsA five case-vignette survey was distributed to head and neck surgical oncologists, medical oncologists, and radiation oncologists who treat head and neck cancer at NCI-Designated Comprehensive Cancer Centers. Providers were asked to recommend management.

resultsEighty-three providers completed the survey (14% response rate). Head and neck surgeons had a 60% surgical recommendation rate while medical and radiation oncologists had a 58% non-surgical recommendation rate. Radiation oncologists were more likely to recommend RT and CRT, and medical oncologists were more likely to recommend CRT over surgery compared to head and neck surgeons.

conclusionsProvider specialty-specific biases influence treatment recommendations and emphasizes the importance of a multidisciplinary approach to head and neck cancer care.

Indexed as

Carcinoma, Squamous CellHuman Papillomavirus VirusesOropharyngeal NeoplasmsPapillomavirus InfectionsPractice Patterns, Physicians'ChemoradiotherapyFemaleHumansMaleMiddle AgedSurveys and Questionnairesdecision‐makinghuman papillomavirusmanagementmultidisciplinaryoropharyngeal cancer

Identifiers

PMID41684065
PMCPMC13432996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.