Evidence map›Paper›PMID 41684050›Full record

ArticleThe Journal of physiology2026

Myosin 7a is required for maintaining the transducing stereocilia and for force transmission to the MET channel during cochlear hair cell development.

Anna Underhill, Samuel Webb, Fiorella C Grandi, Adam J Carlton, Jing-Yi Jeng, Stuart L Johnson, Corné J Kros, Walter Marcotti

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna UnderhillSchool of Biosciences, University of Sheffield, Sheffield, UK.
Samuel WebbSchool of Biosciences, University of Sheffield, Sheffield, UK.
Fiorella C GrandiSorbonne Université, INSERM, Institute de Myologie, Centre de Recherche en Myologie, Paris, France.ORCID 0000-0002-1303-6710
Adam J CarltonSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0000-0002-1054-3901
Jing-Yi JengSchool of Biosciences, University of Sheffield, Sheffield, UK.
Stuart L JohnsonSchool of Biosciences, University of Sheffield, Sheffield, UK.
Corné J KrosSchool of Life Sciences, University of Sussex, Falmer, Brighton, UK.ORCID 0000-0003-1429-4145
Walter MarcottiSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8770-7628

Funding

Biotechnology and Biological Sciences Research Council BB/T004991/1Biotechnology and Biological Sciences Research Council BB/X000567/1Biotechnology and Biological Sciences Research Council BB/Z514743/1Royal National Institute for Deaf People G94Wellcome Trust 224326/Z/21/ZWellcome Trust 300350/Z/23/Z
6 · The paper itself

Abstract

Shaker-1 mice carry a spontaneous missense mutation in Myo7a (Myo7a

Indexed as

Hair Cells, AuditoryMechanotransduction, CellularMyosin VIIaStereociliaAnimalsMiceMyo7a protein, mouseMyosin VIIacochleadeafnesshair cellion channelmechanoelectrical transductionmyosin motor

Identifiers

PMID41684050
PMCPMC12953018

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.