Evidence map›Paper›PMID 41684018›Full record

ArticleInternational journal of molecular sciences2026

3,4-Dihydroxybenzaldehyde Exerts Anti-Alzheimer's Effects by Inhibiting Aβ Protofibril Assembly and Activating Antioxidant Defense Mechanisms.

Zhourong Zhao, Lin Yang, Zhuo Zhang, Jia Song, Chao Zhang, Xiaohua Duan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhourong ZhaoYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.ORCID 0009-0000-3478-1878
Lin YangYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.
Zhuo ZhangYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.
Jia SongYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.
Chao ZhangYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.
Xiaohua DuanYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500, China.

Funding

High-level Talents Projects of Yunnan University of Chinese Medicine-Fifth Level Talents 2023-05-007National Administration of Traditional Chinese Medicine High-level Key Discipline Construction Project 'Dai Medicine' Zyyzdxk-2023193National Natural Science Foundation of China 82560897Xingdian Talent Support Program-Special for Young Talent XDYCQNRC-2022-0284
6 · The paper itself

Abstract

3,4-Dihydroxybenzaldehyde (DBD) is a polyphenolic active constituent derived from

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAntioxidantsBenzaldehydesCatecholsAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA-Binding ProteinsForkhead Transcription FactorsMolecular Dynamics SimulationTranscription FactorsAmyloid beta-PeptidesAntioxidantsBenzaldehydesCaenorhabditis elegans ProteinsCatecholsdaf-16 protein, C elegansDNA-Binding ProteinsForkhead Transcription Factorsprotocatechualdehydeskn-1 protein, C elegansTranscription Factors3,4-dihydroxybenzaldehydeAlzheimer’s diseaseantioxidantAβ protofibrilsCaenorhabditis elegans

Identifiers

PMID41684018
PMCPMC12897862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.