Evidence map›Paper›PMID 41684002›Full record

ArticleInternational journal of molecular sciences2026

Traditional Medicine Extracts of

Khanyisile Mngomezulu, Samukelisiwe Pretty Khathi, Siphathimandla Authority Nkabinde, Magugu Nkabinde, Mlungisi Ngcobo, Nceba Gqaleni

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khanyisile MngomezuluTraditional Medicine, School of Nursing & Public Health, University of KwaZulu-Natal, Howard College, Durban 4001, South Africa.ORCID 0000-0002-5474-4377
Samukelisiwe Pretty KhathiHIV Pathogenesis Programme, University of KwaZulu-Natal, Durban 4041, South Africa.
Siphathimandla Authority NkabindeUngangezulu, Dundee 3000, South Africa.
Magugu NkabindeUngangezulu, Dundee 3000, South Africa.
Mlungisi NgcoboTraditional Medicine, School of Nursing & Public Health, University of KwaZulu-Natal, Howard College, Durban 4001, South Africa.ORCID 0000-0001-8942-1642
Nceba GqaleniTraditional Medicine, School of Nursing & Public Health, University of KwaZulu-Natal, Howard College, Durban 4001, South Africa.ORCID 0000-0003-1946-3120

Funding

National Research Foundation (NRF) Grant number: 121517National Research Foundation (NRF) Grant number: 129916Polio Research Foundation (PRF) Grant number: 19/15South African Medical Research Council Contract 8791/CO MN/22Technology Innovation Agency Contract 2024/FUN081/MWUniversity of KwaZulu-Natal (College of Health Sciences scholarship) Grant number: 643403
6 · The paper itself

Abstract

The persistence of latent HIV-1 reservoirs in individuals on antiretroviral therapy (ART) remains a major barrier to cure, necessitating strategies such as "shock and kill" using latency-reversing agents (LRAs). However, current LRAs show limited clinical efficacy, highlighting the need for novel interventions. This study evaluated the in vitro latency-reversing potential of Product Nkabinde (PN) and

Indexed as

Anti-HIV AgentsHIV-1HIV InfectionsPlant ExtractsVirus LatencyCell LineCell SurvivalHumansPanobinostatTumor Necrosis Factor-alphaVirus ActivationAnti-HIV AgentsPanobinostatPlant ExtractsTumor Necrosis Factor-alphaAfrican traditional medicineHIV-1latencylatency reversal agentsreactivation

Identifiers

PMID41684002
PMCPMC12898761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.